Table 2. Relationship between level of disability, bladder dysfunction, bowel dysfunction, and fatigue.
EDSS: Expanded Disability Status Scale (range 1–10); MFIS: Modified Fatigue Impact Scale (range 1–84); ABSST: Actionable Bladder Symptom Screening Tool (range 1–24); RFIS: Revised Faecal Incontinence Scale (range 1–20).
| Effect | Putative cause | Adjusted for | Effect per unit cause | 95% CI |
|---|---|---|---|---|
| Bladder dysfunction (ABSST)* | Disability (EDSS) | Age | 0.7 | 0.1 to 1.2 |
| Bladder dysfunction (ABSST)* | Fatigue (MFIS) | Disability (EDSS) | 0.10 | 0.05 to 0.14 |
| Faecal incontinence (RFIS)* | Disability (EDSS) | Age | 0.7 | 0.3 to 1.1 |
| Faecal incontinence (RFIS)* | Fatigue (MFIS) | Disability (EDSS) | 0.06 | 0.03 to 0.10 |
| Fatigue (MFIS)** | Disability (EDSS) | Age | 3.6 | 1.7 to 5.5 |
| Fatigue (MFIS)** | Bladder dysfunction (ABSST) | Age | 1.7 | 1.0 to 2.3 |
| Fatigue (MFIS)** | Faecal incontinence (RFIS) | Age | 1.6 | 0.9 to 2.4 |