Table 2. Clinical characteristics of study subjects with and without bacteremia.
No Bacteremia (n = 92) | Bacteremia (n = 26) | P | |
---|---|---|---|
Total counts (cells/1 mL-blood) | 0 | 5.1 ± 4.9 | |
Clinical factors | |||
Sex (male/female) | 58/34 | 17/9 | 0.826 |
Age (years) | 63.6 ± 9.7 | 64.0 ± 9.7 | 0.935 |
Duration of diabetes (years) | 13.6 ± 9.9 | 12.3 ± 7.6 | 0.828 |
Body mass index (kg/m2) | 25.4 ± 4.3 | 25.5 ± 4.3 | 0.843 |
Fasting blood glucose (mg/dL) | 135.9 ± 31.4 | 155.3 ± 47.2 | 0.065 |
HbA1c (%) | 7.7 ± 1.3 | 7.7 ± 1.3 | 0.896 |
C-peptide (ng/mL) | 1.8 ± 0.8 | 2.0 ± 0.7 | 0.211 |
LDL-C (mg/dL) | 114.1 ± 30.0 | 112.1 ± 38.2 | 0.432 |
HDL-C (mg/dL) | 51.4 ± 15.2 | 51.5 ± 14.2 | 0.826 |
TG (mg/dL) | 113.6 ± 47.8 | 118.2 ± 57.0 | 0.937 |
Inflammatory markers | |||
Hs-CRP (mg/dL) | 0.59 ± 1.3 | 0.35 ± 0.3 | 0.843 |
TNF-α (pg/mL) | 1.2 ± 0.6 | 1.3 ± 0.6 | 0.340 |
IL-6 (pg/mL) | 2.0 ± 1.2 | 2.1 ± 1.0 | 0.485 |
LBP (μg/mL) | 11.2 ± 3.5 | 11.2 ± 3.7 | 0.966 |
Fecal organic acids (μmol/g) and pH | |||
Total organic acids | 94.1 ± 40.0 (100) | 89.7 ± 42.9 (100) | 0.600 |
Acetic acid | 56.1 ± 24.4 (100) | 55.5 ± 25.9 (100) | 0.917 |
Propionic acid | 19.4 ± 10.5 (100) | 18.7 ± 10.4 (100) | 0.790 |
Butyric acid | 12.6 ± 8.5 (94.6) | 11.7 ± 9.1 (88.5) | 0.673 |
Isovaleric acid | 3.7 ± 2.5 (63.0) | 2.8 ± 1.5 (61.5) | 0.191 |
Valeric acid | 3.0 ± 1.7 (47.8) | 2.8 ± 1.3 (57.7) | 0.965 |
Succinic acid | 2.7± 5.6 (56.5) | 1.3 ± 1.0 (42.3) | 0.779 |
Lactic acid | 4.3 ± 5.3 (17.4) | 3.2 ± 2.8 (11.5) | NA |
Formic acid | 1.2 ± 1.3 (60.8) | 1.2 ± 1.1 (69.2) | 0.984 |
pH | 6.6 ± 0.7 (100) | 6.6 ± 0.5 (100) | 0.917 |
Data are expressed as mean ± SD. NA: not available, Detection rates are expressed as percentages (%). The lower limit of the measurement of fecal organic acid concentrations (μmol/g): Acetic acid 0.4, Propionic acid 0.5, Butyric acid 0.55, Isovaleric acid 0.8, Valeric acid 0.65, Succinic acid 0.08, Lactic acid 0.2, Formic acid 0.05. See Table 1 for abbreviations.