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. 2019 Sep 19;14(9):e0218144. doi: 10.1371/journal.pone.0218144

Table 3. Results of univariable regression in 83,751 study participants in the UKBB for right and left eye corneal astigmatism.

Significant associations are highlighted in bold. P values for B coefficients are derived from a t-test. 95% CI = 95% confidence interval.

Description Right eye
univariable B (95% CI)
P value Left eye
univariable B (95% CI)
P value
Age, years -0.004 (-0.004 to -0.003) <0.001 -0.004 (-0.005 to -0.004) <0.001
Sex (Ref = F) -0.070 (-0.079 to -0.061) <0.001 -0.080 (-0.089 to -0.071) <0.001
Ethnicity (Ref = white)
asian
-0.081 (-0.104 to -0.058) <0.001 -0.102 (-0.126 to -0.079) <0.001
black -0.061 (-0.086 to -0.036) <0.001 -0.068 (-0.093 to -0.043) <0.001
mixed -0.017 (-0.063 to 0.028) 0.45 -0.018 (-0.064 to 0.028) 0.447
chinese -0.022 (-0.089 to 0.044) 0.515 -0.040 (-0.108 to 0.027) 0.243
Age completed full time education 0.004 (0.002 to 0.006) 0.001 0.005 (0.003 to 0.007) <0.001
Skin colour, lighter to darker* -0.029 (-0.034 to -0.024) <0.001 -0.030 (-0.035 to -0.026) <0.001
Use of UV protection 0.017 (0.013 to 0.022) <0.001 0.016 (0.011 to 0.020) <0.001
Alcohol intake, never to daily** -0.009 (-0.012 to -0.006) <0.001 -0.009 (-0.012 to -0.007) <0.001
Season of assessment (baseline = spring)
autumn
-0.005 (-0.016 to 0.006) 0.387 -0.011 (-0.023 to 0.000) 0.055
winter -0.007 (-0.019 to 0.004) 0.212 -0.006 (-0.018 to 0.006) 0.324
summer 0.017 (0.005 to 0.029) 0.005 0.014 (0.002 to 0.026) 0.026
Corneal-compensated IOP, mmHg -0.006 (-0.007 to -0.005) <0.001 -0.007 (-0.008 to -0.006) <0.001
Corneal resistance factor -0.003 (-0.005 to -0.002) <0.001 -0.001 (-0.003 to 0.001) 0.35
Corneal hysteresis 0.003 (0.001 to 0.005) 0.004 0.006 (0.004 to 0.007) <0.001
Height, m -0.002 (-0.002 to -0.002) <0.001 -0.002 (-0.002 to -0.001) <0.001
Weight, 10 kg -0.000 (-0.001 to -0.000) 0.012 -0.000 (-0.001 to -0.000) 0.044
BMI, kg/m2 0.001 (0.000 to 0.002) 0.021 0.001 (0.000 to 0.002) 0.011
SBP, mmHg -0.001 (-0.001 to -0.001) <0.001 -0.001 (-0.001 to -0.001) <0.001
DBP, mmHg -0.001 (-0.001 to -0.000) 0.001 -0.001 (-0.001 to -0.000) <0.001
Townsend deprivation index 0.003 (0.001 to 0.004) <0.001 0.003 (0.002 to 0.005) <0.001
Smoker (baseline = false) -0.011 (-0.025 to 0.004) 0.144 -0.012 (-0.026 to 0.003) 0.112
Age Asthma Diagnosed, self-reported -0.001 (-0.002 to -0.000) 0.014 -0.001 (-0.002 to -0.000) 0.014
Diabetes, doctor diagnosed (baseline = false) -0.023 (-0.042 to -0.004) 0.018 -0.006 (-0.025 to 0.014) 0.561

* Skin colour is coded as: very fair = 1, fair = 2, light olive = 3, dark olive = 4, brown = 5, black = 6

** Alcohol intake is coded as: never = 0, special occasions = 1, one to three times a month = 2, once twice a week = 3, three four times a week = 4, daily = 5.