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. 2019 Sep 19;14(9):e0218144. doi: 10.1371/journal.pone.0218144

Table 4. Results of multivariable regression in 83,751 study participants in the UKBB for right and left eye corneal astigmatism.

Only parameters that were significant in the univariable regression were included in the multivariable regression. Significant associations are highlighted in bold. P values for B coefficients are derived from a t-test. 95% CI = 95% confidence interval.

Description Right eye
multivariable B (95% CI)
P value Left eye
multivariable B (95% CI)
P value
Age, years -0.004 (-0.004 to -0.003) <0.001 -0.004 (-0.004 to -0.003) <0.001
Sex (Ref = F) -0.053 (-0.070 to -0.037) <0.001 -0.079 (-0.095 to -0.062) <0.001
Ethnicity (Ref = white) asian -0.026 (-0.065 to 0.014) 0.208 -0.072 (-0.113 to -0.032) <0.001
black 0.015 (-0.030 to 0.061) 0.508 -0.018 (-0.064 to 0.028) 0.448
mixed -0.064 (-0.126 to -0.002) 0.044 -0.032 (-0.095 to 0.032) 0.327
chinese -0.088 (-0.188 to 0.012) 0.085 -0.079 (-0.181 to 0.023) 0.127
Age completed full time education 0.005 (0.002 to 0.007) <0.001 0.005 (0.003 to 0.008) <0.001
Skin colour, lighter to darker* -0.033 (-0.042 to -0.024) <0.001 -0.028 (-0.037 to -0.019) <0.001
Use of UV protection 0.007 (0.001 to 0.013) 0.031 0.000 (-0.006 to 0.007) 0.901
Alcohol intake, never to daily** -0.008 (-0.012 to -0.004) <0.001 -0.007 (-0.011 to -0.003) <0.001
Corneal-compensated IOP, mmHg -0.005 (-0.006 to -0.004) <0.001 -0.006 (-0.008 to -0.005) <0.001
Corneal resistance factor -0.006 (-0.008 to -0.003) <0.001
Corneal hysteresis -0.003 (-0.005 to -0.000) 0.037
Height, m -0.001 (-0.002 to -0.000) 0.042 -0.000 (-0.001 to 0.001) 0.742
SBP, mmHg -0.000 (-0.000 to 0.000) 0.702 -0.000 (-0.001 to 0.000) 0.258
DBP, mmHg 0.001 (0.000 to 0.002) 0.021 0.001 (0.000 to 0.001) 0.038
Townsend deprivation index 0.004 (0.002 to 0.006) <0.001 0.004 (0.002 to 0.006) <0.001

* Skin colour is coded as: very fair = 1, fair = 2, light olive = 3, dark olive = 4, brown = 5, black = 6

** Alcohol intake is coded as: never = 0, special occasions = 1, one to three times a month = 2, once twice a week = 3, three four times a week = 4, daily = 5.