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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Adv Healthc Mater. 2019 Aug 12;8(18):e1900506. doi: 10.1002/adhm.201900506

Figure 1.

Figure 1.

Alginate-based hydrogels in tissue engineering applications. (a) The use of alginate for engineering IPN hydrogels with various materials or its use as a sacrificial network for creating fibers from polymers and protein-based hydrogels. (b) SEM image of IPN fibers of GelMA and alginate (left) and the removal of alginate from the construct to fabricate pure GelMA fibers (right). (c) Cellular morphology shown by F-actin staining in IPN fibers of GelMA and alginate (left) and GelMA fibers after the removal alginate from the network (right). Reproduced with permission.[62] Copyright 2015, John Wiley and Sons. (d) The use of alginate for carrying PRP as a source of biological factors in tissue engineering. The hydrogel fibers could be printed in the presence of CaCl2 mist on dry substrates. (e) The effect of PRP encapsulated in alginate in releasing angiogenic factors facilitating vascularization. Reproduced with permission.[6] Copyright 2018, John Wiley and Sons.