Table 2.
Incidence rate per person-year (95% CI) |
7-day primaquine vs control |
14-day primaquine vs control |
7-day primaquine vs 14-day primaquine |
||||||
---|---|---|---|---|---|---|---|---|---|
Placebo (n=464) | 7-day primaquine (n=935) | 14-day primaquine (n=937) | Incidence rate ratio | p value | Incidence rate ratio | p value | Incidence rate ratio | p value | |
Total patient days of follow-up* | 139 258 | 279 371 | 287 200 | .. | .. | .. | .. | .. | .. |
Symptomatic Plasmodium vivax parasitaemia | 0·96 (0·83–1·08) | 0·18 (0·15–0·21) | 0·16 (0·13–0·18) | 0·20 (0·15–0·28) | <0·0001 | 0·18 (0·13–0·24) | <0·0001 | 1·19 (0·92–1·53) | 0·18 |
Any Plasmodium vivax parasitaemia | 1·32 (1·16–1·48) | 0·23 (0·19–0·27) | 0·19 (0·16–0·23) | 0·19 (0·14–0·27) | <0·0001 | 0·16 (0·12–0·23) | <0·0001 | 1·17 (0·92–1·48) | 0·21 |
Any Plasmodium falciparum parasitaemia | 0·10 (0·05–0·15) | 0·15 (0·11–0·19) | 0·10 (0·07–0·14) | 1·22 (0·80–1·85) | 0·36 | 0·97 (0·63–1·49) | 0·89 | 1·25 (0·89–1·76) | 0·19 |
Parasitaemia of any species | 1·42 (1·25–1·59) | 0·38 (0·32–0·44) | 0·30 (0·24–0·35) | 0·25 (0·19–0·33) | <0·0001 | 0·21 (0·16–0·27) | <0·0001 | 1·23 (0·99–1·52) | 0·061 |
From the first visit to the end of follow-up, or until the last visit if lost.