Table 1.
Characteristic | Statin non-users | Statin users | ORa | 95% CI | P-value (trend) | ||
---|---|---|---|---|---|---|---|
n | % | n | % | ||||
Age | |||||||
18–55 years | 13076 | 17.6 | 1778 | 3.2 | 1 | ||
55–65 years | 17948 | 24.2 | 8793 | 16.0 | 3.59 | 3.40–3.80 | |
65–75 years | 17945 | 24.2 | 17560 | 31.9 | 7.17 | 6.79–7.56 | |
75–85 years | 18065 | 24.4 | 20912 | 38.0 | 8.50 | 8.06–8.97 | |
85–95 years | 7075 | 9.5 | 5965 | 10.8 | 6.23 | 5.86–6.62 | <0.0001 |
Sex | |||||||
Male | 43557 | 58.8 | 33112 | 60.2 | 1 | ||
Female | 30552 | 41.2 | 21896 | 39.8 | 0.93 | 0.91–0.96 | <0.0001 |
Year of entry (years) | |||||||
2010 | 12871 | 17.4 | 7743 | 14.1 | 1 | ||
2011 | 12913 | 17.4 | 8426 | 15.3 | 1.11 | 1.07–1.16 | |
2012 | 12884 | 17.4 | 9582 | 17.4 | 1.24 | 1.19–1.29 | |
2013 | 12754 | 17.2 | 10297 | 18.7 | 1.33 | 1.28–1.38 | |
2014 | 12858 | 17.4 | 10500 | 19.1 | 1.38 | 1.33–1.44 | |
2015 | 9829 | 13.3 | 8460 | 15.4 | 1.43 | 1.37–1.49 | <0.0001 |
Body Mass Index | |||||||
≤25 kg/m2 | 12217 | 16.5 | 8769 | 15.9 | 1 | ||
25.1–30.0 kg/m2 | 47902 | 64.6 | 29691 | 54.0 | 0.91 | 0.88–0.94 | |
>30 kg/m2 | 13990 | 18.9 | 16548 | 30.1 | 1.67 | 1.61–1.73 | <0.0001 |
Tobacco b | |||||||
Non-smoker | 35247 | 61.3 | 31761 | 61.0 | 1 | ||
Current smoker | 10875 | 18.9 | 6608 | 12.7 | 0.94 | 0.91–0.98 | |
Former smoker | 11392 | 19.8 | 13701 | 26.3 | 1.42 | 1.38–1.47 | |
Alcohol b | |||||||
None/mild | 30591 | 63.1 | 30927 | 64.5 | 1 | ||
Moderate | 16524 | 34.1 | 16010 | 33.4 | 1.02 | 0.99–1.05 | |
Severe | 1387 | 2.9 | 1045 | 2.2 | 0.89 | 0.81–0.96 | 0.004 |
NSAIDs | |||||||
Non-users | 31529 | 42.5 | 8525 | 15.5 | 1 | ||
Users | 42580 | 57.5 | 46483 | 84.5 | 3.61 | 3.51–3.71 | <0.0001 |
aAdjusted for age and sex.
bVariables with missing data.
NSAID: Nonsteroidal anti-inflammatory drugs