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. 2019 Sep 19;9:13560. doi: 10.1038/s41598-019-49877-5

Table 1.

Characteristics of the study according to statin use (controls only, N = 129117).

Characteristic Statin non-users Statin users ORa 95% CI P-value (trend)
n % n %
Age
18–55 years 13076 17.6 1778 3.2 1
55–65 years 17948 24.2 8793 16.0 3.59 3.40–3.80
65–75 years 17945 24.2 17560 31.9 7.17 6.79–7.56
75–85 years 18065 24.4 20912 38.0 8.50 8.06–8.97
85–95 years 7075 9.5 5965 10.8 6.23 5.86–6.62 <0.0001
Sex
Male 43557 58.8 33112 60.2 1
Female 30552 41.2 21896 39.8 0.93 0.91–0.96 <0.0001
Year of entry (years)
2010 12871 17.4 7743 14.1 1
2011 12913 17.4 8426 15.3 1.11 1.07–1.16
2012 12884 17.4 9582 17.4 1.24 1.19–1.29
2013 12754 17.2 10297 18.7 1.33 1.28–1.38
2014 12858 17.4 10500 19.1 1.38 1.33–1.44
2015 9829 13.3 8460 15.4 1.43 1.37–1.49 <0.0001
Body Mass Index
≤25 kg/m2 12217 16.5 8769 15.9 1
25.1–30.0 kg/m2 47902 64.6 29691 54.0 0.91 0.88–0.94
>30 kg/m2 13990 18.9 16548 30.1 1.67 1.61–1.73 <0.0001
Tobacco b
Non-smoker 35247 61.3 31761 61.0 1
Current smoker 10875 18.9 6608 12.7 0.94 0.91–0.98
Former smoker 11392 19.8 13701 26.3 1.42 1.38–1.47
Alcohol b
None/mild 30591 63.1 30927 64.5 1
Moderate 16524 34.1 16010 33.4 1.02 0.99–1.05
Severe 1387 2.9 1045 2.2 0.89 0.81–0.96 0.004
NSAIDs
Non-users 31529 42.5 8525 15.5 1
Users 42580 57.5 46483 84.5 3.61 3.51–3.71 <0.0001

aAdjusted for age and sex.

bVariables with missing data.

NSAID: Nonsteroidal anti-inflammatory drugs