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. 2019 Sep 13;13:962. doi: 10.3389/fnins.2019.00962

FIGURE 4.

FIGURE 4

Neurotrophin expression and neurogenesis at P21. Relative gene expression compared to controls (= 1.0) at P21, CO n = 8, HFD n = 8. (A) Hypothalamic neurotrophins Bdnf, Ngf, Nt3, Nt4/5, Cntf, and Gdnf and (B) hypothalamic neurotrophin receptors TrkA, TrkB, TrkC, and p75Ntr. (C) Rest brain neurotrophins Bdnf, Ngf, Nt3, Nt4/5, Cntf, and Gdnf and (D) rest brain neurotrophin receptors TrkA, TrkB, TrkC, and p75Ntr. (E,F), Representative Western Blots of DCX and PCNA in hypothalamic tissue at P21. (E,F), Densitometric analysis of protein expression at P21: (E) DCX/GAPDH, CO n = 5, HFD n = 5. (F) PCNA/GAPDH, CO n = 5, HFD n = 5. Data are presented as mean ± SEM. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001; CO, control; HFD, high fat diet.