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. 2019 Sep 13;10:1157. doi: 10.3389/fphys.2019.01157

TABLE 2.

KIM-1 and NGAL mRNA levels (arbitrary units) in BUO, B-R1D, and B-R3D kidney with or without aliskiren treatment.

KIM-1 NGAL
Sham 1 ± 0.3 1 ± 0.3
BUO 446 ± 45.2 167 ± 51.5
BUO + Ali 236 ± 3.2# 152 ± 10.6

Sham 1 ± 0.1 1 ± 0.2
B-R1D 152 ± 6.9 112 ± 21.4
B-R1D + Ali 125 ± 13.4 34.5 ± 5.8#

Sham 1 ± 0.2 1 ± 0.2
B-R3D 19.4 ± 2.6 16.6 ± 3.9
B-R3D + Ali 18.9 ± 1.6 15.3 ± 1.4

KIM-1, kidney injury molecule-1; NGAL, neutrophil gelatinase-associated lipocalin; Sham, sham-operated groups; BUO, bilateral ureteral obstruction for 24 h; B-R1D, bilateral ureteral obstruction for 16 h followed by 1 day release; B-R3D, bilateral ureteral obstruction for 16 h followed by 3 days release. p < 0.05 compared with Sham group; #p < 0.05 compared with obstructed kidney group.