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. 2019 Sep 13;13:417. doi: 10.3389/fncel.2019.00417

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Copyright © 2019 Faynveitz, Lavian, Jacob and Korngreen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Dopamine depletion decreased the intrinsic excitability of GABA neurons. (A) The spontaneous activity of neurons from naïve rats was higher than the activity of neurons from dopamine depleted rats. (B) The spontaneous activity of neurons from naïve rats was more regular than the activity of neurons from dopamine depleted rats. (C) Spontaneous firing rate distribution recorded from naïve (Ci) and parkinsonian rats (Cii). (D) Firing frequency as a function of current injection. Straight lines are linear curve fits to the rise phase of the curves. Values are expressed as the mean ± SEM. *p < 0.05, Mann–Whitney U-test.