Table 4.
Fusion genes identified in grade II and grade IV spinal cord gliomas.
| Sample ID | Fusion Gene | LeftBreakpoint | RightBreakpoint | Verified By RT-PCR |
|---|---|---|---|---|
| S01(Grade II) | RNF213-SLC26A11 | chr17:78324196 | chr17:78221929 | No |
| S01/S02/S03/S04(Grade II) | GATSL2-GTF2I | chr7:74867229 | chr7:74143124 | Yes |
| S03(Grade II) | KIAA1549-BRAF | chr7:138552721 | chr7:140487384 | Yes |
| S06(Grade IV) | RC3H1-PKLR | chr1:173947626 | chr1:155260469 | No |
| S06(Grade IV) | MEX3B-KIAA1199 | chr15:82337791 | chr15:81212435 | Yes |
| S08(Grade IV) | ABL2-NCF2 | chr1:179095512 | chr1:183529408 | Yes |
| S09(Grade IV) | CASK-SUGP1 | chrX:41646431 | chr19:19427402 | No |
| S09(Grade IV) | TMEM165-PDGFRA | chr4:56262563 | chr4:55133456 | No |
| S09(Grade IV) | SLC35F1-ECHDC1 | chr6:118588317 | chr6:127611422 | Yes |
| S09(Grade IV) | TCF12-SCFD2 | chr15:57213296 | chr4:54140168 | Yes |
| S06(Grade IV) | CPD-SEZ6 | chr17:28712254 | chr17:27284557 | No |
Note:
Left Break point: The genome position where the upstream gene break point is located.
Right Break point: The genome position where the downstream genes break points is located.
Verified By RT-PCR: “Yes” mean that the fusion genes were verified by RT-PCR sucessfully, and “No” mean that the fusion genes were not verified by RT-PCR successfully.