Table 4.

Phenotypic spectrum of patients with KCNQ2, SCN2A, or PRRT2 pathogenic variants.

	PRRT2 (n = 10)	KCNQ2 (n = 5)	SCN2A (n = 4)
Epilepsy syndrome
	Benign familial infantile (n = 5)	Benign familial neonatal (n = 2)	Ohtahara syndrome (n = 1) Unclassified (n = 3)
	Benign infantile (n = 3)	Ohtahara syndrome (n = 1)
	Unclassified (n = 2)	Unclassified (n = 2)
Drug responsiveness
Self-limited	8	3	1
Drug responsive	2	1	1
Drug resistant		1	2
Developmental disability
Normal	8	3	0
Intellectual disability	1	2	3
ADHD*/ASD*	1	0	1

^*ADHD, attention deficit hyperactivity disorder; ASD, autism spectrum disorder.