Table 3. Diagnostic characteristics for evaluating CMSA and its early stage using three methods.

	CMSA			Early stage of CMSA
	ccPWV (m/s)	cIMT (mm)	baPWV (m/s)	ccPWV (m/s)	cIMT (mm)	baPWV (m/s)
AUC	0.887*	0.786*	0.606*	0.815†	0.730†	0.475†
(95% CI)	(0.835, 0.938)	(0.711, 0.861)	(0.517, 0.695)	(0.729, 0.902)	(0.630, 0.830)	(0.354, 0.596)
P Value	< 0.001	< 0.001	0.027	< 0.001	< 0.001	0.668
Sensitivity,%	70.1	67.7	55.2	86	58.1	48.8
Specificity,%	93.1	82.8	74.1	70.7	82.8	63.8
Youden's index	0.639	0.505	0.293	0.567	0.409	0.126
Cutpoint	5.8	0.95	15.7	5.4	0.95	14.8

^*†P ≤ 0.001.

CMSA indicates the segment atherosclerosis between common carotid artery and the ipsilateral middle cerebral artery; ccPWV, carotid–cerebral pulse wave velocity; cIMT, carotid intima-media thickness; baPWV, brachium-ankle pulse wave velocity; AUC, area under the curve; CI, confidence interval.