Table 3.
Outcome parameters of the study groups
| Outcome parameter | Group A (n=25) | Group B (n=26) | P valuea) |
|---|---|---|---|
| MV mode | |||
| Day 1 | |||
| SIMV | 21 (84) | 24 (92.3) | 0.31 |
| HFOV | 2 (8) | 1 (3.8) | |
| PRVC | 2 (8) | 0 (0) | |
| ET-CPAP | 0 (0) | 1 (3.8) | |
| Day 7 | |||
| SIMV | 10 (40) | 9 (34.6) | 0.81 |
| HFOV | 1 (4) | 1 (3.8) | |
| PRVC | 1 (4) | 0 (0) | |
| PSV | 0 (0) | 1 (3.8) | |
| ET-CPAP | 2 (8) | 3 (11.5) | |
| P valueb) | 0.001 | 0.000 | |
| Assisted minute ventilation (L/m2/ min) | |||
| Day 1 | 5.86 (3.6–8.9) | 4.52 (3.3–6.9) | 0.23 |
| Day 7 | 6.19 (4.7–7.8) | 8.17 (4.5–10.8) | 0.36 |
| P valueb) | 0.08 | 0.74 | |
| pH | |||
| Day 1 | 7.37±0.1 | 7.46±0.1 | 0.06 |
| Day 7 | 7.46±0.1 | 7.45±0.1 | 0.71 |
| P valueb) | 0.004 | 0.81 | |
| pCO2 | |||
| Day 1 | 47±15.1 | 42.24±15.9 | 0.11 |
| Day 7 | 37.98±8.3 | 42.14±13.4 | 0.22 |
| P valueb) | 0.006 | 0.97 | |
| Albumin (g/dL) | |||
| Day 1 | 3.4 (2.8–3.7) | 3.65 (3.1–4.3) | 0.04 |
| Day 7 | 3.1 (2.8–3.5) | 3.45 (2.7–3.8) | 0.07 |
| P valueb) | 0.11 | 0.004 | |
| Prealbumin (mg/dL) | |||
| Day 1 | 8.25 (4.5–11.5) | 11.05 (7.2–13.4) | 0.23 |
| Day 7 | 11.75 (8.7–20.7) | 15.1 (11.4–19.2) | 0.52 |
| P valueb) | 0.002 | 0.19 | |
| Triglycerides (mg/dL) | |||
| Day 1 | 165 (74–232) | 150 (127.3–199.3) | 0.95 |
| Day 7 | 216.5 (173.8–346) | 158 (151–257) | 0.11 |
| P valueb) | 0.005 | 0.41 | |
| Nutritional facts at day 7 | |||
| % proteins achieved | 50 (48.8–75) | 50 (33.3–100) | 0.62 |
| % calories achieved | 60 (40–83) | 49.5 (23.8–100) | 0.75 |
| Day-7 outcomes | |||
| Extubated | 8 (32) | 7 (27) | |
| Not extubated | 15 (60) | 15 (57.6) | 0.70 |
| Dead | 2 (8) | 4 (15.4) | |
| Day-14 outcome | |||
| Extubated | 9 (36) | 2 (7.6) | 0.03* |
| Not extubated | 10 (40) | 12 (46) | |
| Dead | 4 (16) | 10 (38.4) | |
| Final outcome | |||
| Death | 12 (48) | 18 (69.2) | 0.16 |
| Discharge | 11 (44) | 5 (19.2) | |
| Admitted | 2 (8) | 3 (11.5) |
Values are presented as number (%), median (interquartile range), or mean±standard deviation.
Group A, high fat feeding group; group B, standard feeding group; MV, mechanical ventilation; SIMV, synchronized intermittent mandatory ventilation; HOFV, high-frequency oscillatory ventilation; PRVC, pressure regulated volume control; PSV, pressure support ventilation; ET-CPAP, endotracheal continuous positive airway pressure.
a)
P value for differences between the groups A and B.
b)
P value for differences before and after the intervention (day 1 and day 7 of enrollment) for each group.
Boldface indicates a statistically significant difference with P<0.05.