Table 3. Univariate Analysis for Progression Free Survival (PFS) and Overall Survival (OS).
| Molecule | n | Median PFS (month) (95% CI) | p value | Median OS (month) (95% CI) | p value |
|---|---|---|---|---|---|
| Gli1 | 0.547 | 0.867 | |||
| No | 24 | 6.9 (5.8–8.0) | 11.7 (8.4–15.0) | ||
| Yes | 12 | 6.7 (5.0–8.4) | 9.5 (6.8–12.2) | ||
| Patched | 0.701 | 0.692 | |||
| No | 31 | 7.6 (5.4–9.7) | 11.7 (8.8–14.6) | ||
| Yes | 5 | 6.7 (6.5–6.9) | 10.9 (8.0–13.8) | ||
| Shh | 0.005 | 0.039 | |||
| No | 31 | 7.6 (5.7–9.5) | 12.0 (7.2–16.8) | ||
| Yes | 5 | 6.3 (0.0–17.5) | 9.2 (0.0–27.6) | ||
| Smo | 0.437 | 0.769 | |||
| No | 30 | 6.9 (5.5–8.4) | 11.7 (8.2–15.2) | ||
| Yes | 6 | 6.0 (4.7–7.3) | 9.1 (4.7–13.4) |
CI, confidence interval; Gli1, Glioma-associated oncogene homolog zinc finger protein 1; Shh, sonic hedgehog; Smo, Ptch-mediated repression of smoothened.