Table 1. Demographic and Clinical Characteristics of Participants at Baseline.
| Total participants | Followed for 1 year only | |||
|---|---|---|---|---|
| aMCI Aβ− (n=230) | aMCI Aβ+ (n=268) | aMCI Aβ− (n=156) | aMCI Aβ+ (n=253) | |
| Age (yr) | 70.95 (8.32) | 73.69 (7.14)* | 71.53 (8.45) | 73.71 (6.99)* |
| Education (yr) | 16.34 (2.48) | 15.94 (2.87) | 16.62 (2.42) | 15.86 (2.88)* |
| Female (n, %) | 127 (55.2) | 154 (57.5) | 63 (40.4) | 107 (42.3) |
| APOE ε4 carriers (n, %) | 54 (23.5) | 173 (64.6)* | 41 (26.3) | 167 (66.0)* |
| Aβ | 1.00 (0.53) | 1.37 (0.17)* | 1.01 (0.55) | 1.37 (0.17)* |
| CDR-SOB | 1.32 (0.83) | 1.63 (0.98)* | 1.34 (0.86) | 1.65 (0.96)* |
| FAQ | 1.97 (3.18) | 3.29 (4.07)* | 2.15 (3.28) | 3.43 (4.14)* |
| MMSE | 28.52 (1.45) | 27.64 (1.84)* | 28.60 (1.48) | 27.60 (1.85)* |
| ADNI-EF | 0.53 (0.73) | 0.18 (0.82)* | 0.48 (0.74) | 0.16 (0.81)* |
aMCI Aβ−, amnestic mild cognitive impairment with low Aβ burden; aMCI Aβ+, amnestic mild cognitive impairment with high Aβ burden; APOE, apolipoprotein E; Aβ, florbetapir mean standard uptake value ratio of frontal, anterior cingulate, precuneus and parietal cortex relative to the cerebellum; CDR-SOB, Clinical Dementia Rating sum of boxes; FAQ, Functional Assessment Questionnaire; MMSE, Mini Mental Status Examination; ADNI-EF, Alzheimer's Disease Neuroimaging Initiative composite score for executive function.
Data are presented as mean (standard deviation) unless specified otherwise.
*p<0.05.