Table 2.
Summary of Treatment Outcomes for all Included Studies and for Studies that Delivered hSRT in 2-5 Fractions
| Outcome | All Included Studies (n = 14; Pts = 630) | Studies with hSRT in 2-5 Fractions (n = 9; Pts = 331) | ||||
|---|---|---|---|---|---|---|
| % | n | Pts | % | n | Pts | |
| Clinical Response | ||||||
| Median | 45 | 43 | ||||
| Range | 18-87 | 11 | 482 | 18-87 | 7 | 275 |
| Mean | 51 | 46 | ||||
| Radiographic Response | ||||||
| Median | 14 | 22 | ||||
| Range | 6-41 | 10 | 469 | 9-41 | 6 | 262 |
| Mean | 19 | 23 | ||||
| Radiographic Stability | ||||||
| Median | 78 | 70 | ||||
| Range | 59-92 | 10 | 469 | 59-90 | 6 | 262 |
| Mean | 76 | 71 | ||||
| Crude Local Control | ||||||
| Median | 100 | 100 | ||||
| Range | 90-100 | 10 | 407 | 90-100 | 8 | 312 |
| Mean | 97 | 97 | ||||
| 3-Year PFS | ||||||
| Median | 92 | 94 | ||||
| Range | 89-100 | 3 | 254 | 89-100 | 2 | 162 |
| Mean | 94 | 94 | ||||
| 5-Year PFS | ||||||
| Median | 88 | 90 | ||||
| Range | 81-98 | 4 | 323 | 87-93 | 2 | 174 |
| Mean | 89 | 90 | ||||
Abbreviations: hSRT, hypofractionated stereotactic radiotherapy; PFS, progression-free survival; Pts, patients.