Table 2.
Association between Nectin-4 expression and clinicopathological parameters.
| Clinicopathologic parameter | Nectin-4 high | Nectin-4 low | p-value | ||
|---|---|---|---|---|---|
| Mean tumor size (mm) ± SD | 25 ± 20 | 30 ± 20 | 0.125 | ||
| Mean age at diagnosis (years) ± SD | 64 ± 14 | 60.5 ± 15 | 0.765 | ||
| (n) | (%) | (n) | (%) | ||
| Tumor stage | 0.025 | ||||
| pT1 | 28 | 32.9 | 1 | 3.8 | |
| pT2 | 43 | 50.6 | 18 | 69.2 | |
| pT3 | 8 | 9.4 | 3 | 11.5 | |
| pT4 | 6 | 7.1 | 4 | 15.5 | |
| Lymph node involvement | 0.034 | ||||
| pN0 | 42 | 64.0 | 14 | 49.5 | |
| pN1 | 28 | 31.3 | 4 | 39.4 | |
| pN2 | 5 | 4.7 | 6 | 11.1 | |
| pN3 | 7 | 0.0 | 1 | 0.0 | |
| Tumor grade | 0.722 | ||||
| 1 | 2 | 2.3 | 0 | 0.0 | |
| 2 | 15 | 17.4 | 5 | 20.0 | |
| 3 | 69 | 80.3 | 20 | 80.0 | |