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. 2019 Sep 13;10:1015. doi: 10.3389/fphar.2019.01015

Figure 4.

Figure 4

Systemic infusion of IL-17A in mice induces kidney inflammation. Inflammatory cell infiltration was characterized by immunohistochemistry using antibodies for monocyte/macrophages (F4/80), lymphocytes (CD3, CD4, and γδ), neutrophils (myeloperoxidase, MPO), and mast cells (tryptase). (A) Representative immunohistochemistry images of IL-17A-infused and control mice. (B) and (C). Inflammatory cell staining was quantified as the percentage of total kidney area that was stained. Data are expressed as mean ± S.E.M. of 6–8 mice per group. *p < 0.05 vs. control.