Table 3. Protocol outcomes.

Outcome	Pre-protocol (n=72)	Post-protocol (n=51)	P value
aPTT time in therapeutic range (%)	29±21	25±17	0.28
Heparin dosage (units/kg/h)*	10.1±5.0	9.4±5.1	0.49
Time to therapeutic anticoagulation (h)†	17.8±12.8	16.5±10.4	0.59

Data are presented as mean ± SD or as %. *, average dosage after 48 hours of heparin initiation; ^†, therapeutic anticoagulation defined as time to first therapeutic aPTT of 60–80 seconds or TEG of 2–4× baseline. aPTT, activated partial thromboplastin time; SD, standard deviation; TEG, thromboelastography.