Table 3. Relationship between serum adipocytokines levels (pg/mL) and clinicopathological features of lung cancer.

Clinicopathological parameters	IGFBP-1	TNF RI	VEGF	TNF RII	BDNF	PAI-1	IL-6
Histology
Adenocarcinoma	158,243	47,944	12,449	55,344	55,768	14,434	12,452
Squamous cell	175,741	40,599	12,483	46,102	42,168	12,497	12,135
Small cell carcinoma	99,137	46,050	11,058	49,454	48,045	12,320	12,652
P value	0.24	0.63	0.96	0.82	0.74	0.89	0.73
Tumor size
≤3 cm	142,571	43,508	12,378	42,374	65,235	16,820	13,377
3–5 cm	150,059	35,629	9,223	48,704	44,592	11,894	11,463
>5 cm	153,325	51,301	13,530	56,805	43,361	12,054	12,238
P value	0.95	0.10	0.48	0.64	0.42	0.65	0.19
Lymphatic metastasis
Positive	150,259	46,861	11,898	51,247	47,688	13,936	12,194
Negative	140,549	38,617	12,826	49,482	56,015	10,753	13,193
P value	0.83	0.36	0.88	0.94	0.44	0.05	0.61
Distant metastasis
Yes	151,356	50,511	13,633	53,130	56,360	12,620	12,597
No	143,895	36,783	9,977	47,775	46,193	14,539	12,140
P value	0.05	0.03	0.33	0.10	0.57	0.30	0.27
TNM stage
I	147,430	30,024	12,086	43,820	56,692	11,614	12,300
II	172,561	49,723	5,652	58,446	32,619	23,094	12,955
III	108,157	37,363	10,084	45,015	38,771	11,836	11,005
IV	151,356	50,511	13,633	53,130	56,360	12,620	12,597
P value	0.31	0.08	0.37	0.16	0.32	0.71	0.07

Median values are given. Using the Kruskal-Wallis test calculate the P values). BMI, body mass index; NS Non-significant. IGFBP-1, insulin-like growth factor binding protein 1; TNF, tumor necrosis factor; VEGF, vascular endothelial growth factor; IL, interleukin; BDNF, brain-derived neurotrophic factor; PAI-1, plasminogen activator inhibitor-1.