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. 2019 Aug;11(8):3449–3458. doi: 10.21037/jtd.2019.07.73

Table 2. Univariate analysis of clinical-pathologic potential prognostic factors.

Patient characteristics 5-year overall survival 5-year disease-free survival
Rate (%) P value Rate (%) P value
Sex 0.880 0.560
   Male 59.7 58.1
   Female 53.4 46.1
Tumor location 0.670 0.830
   Right 52.8 55.6
   Left 59.6 48.3
Histology 0.0015 0.0002
   Squamous cell carcinoma 71.8 67.3
   Adenocarcinoma 49.9 47.2
   Large-cell carcinoma 25.0 16.7
Type of resection 0.190 0.321
   Sublobar resection 37.5 37.5
   Lobectomy 55.5 50.9
   Pneumonectomy 68.7 62.5
Compartment of lymph node metastases
   Hilar, yes/no 55.2/58.9 0.709 53.8/47.7 0.417
   Interlobar, yes/no 59.6/44.0 0.241 55.3/39.7 0.195
   Pulmonary, yes/no 52.8/59.2 0.260 46.7/55.6 0.296
Extranodal lymph node involvement 0.570 0.399
   Yes 59.3 56.8
   No 54.6 49.0
Lymph node involvement due to 0.350 0.880
   Direct tumor involvement 59.5 52.2
   Metastatic lymph node involvement 53.2 51.0
Number of lymph node metastases 0.126 0.045
   Single 64.5 62.9
   Multiple 49.3 42.3
Central tumor location (<2 cm) 0.170 0.386
   Yes 62.3 56.9
   No 50.3 47.1
T descriptor 0.580 0.460
   pT1 59.1 56.0
   pT2 55.5 50.1
UICC stage 0.051 0.011
   IIA 63.0 60.0
   IIB 38.9 31.1
Adjuvant chemotherapy 0.560 0.639
   Yes 57.9 53.9
   No 55.2 50.3

UICC, Union for International Cancer Control.