Table 2. Univariate analysis of clinical-pathologic potential prognostic factors.
Patient characteristics | 5-year overall survival | 5-year disease-free survival | |||
---|---|---|---|---|---|
Rate (%) | P value | Rate (%) | P value | ||
Sex | 0.880 | 0.560 | |||
Male | 59.7 | 58.1 | |||
Female | 53.4 | 46.1 | |||
Tumor location | 0.670 | 0.830 | |||
Right | 52.8 | 55.6 | |||
Left | 59.6 | 48.3 | |||
Histology | 0.0015 | 0.0002 | |||
Squamous cell carcinoma | 71.8 | 67.3 | |||
Adenocarcinoma | 49.9 | 47.2 | |||
Large-cell carcinoma | 25.0 | 16.7 | |||
Type of resection | 0.190 | 0.321 | |||
Sublobar resection | 37.5 | 37.5 | |||
Lobectomy | 55.5 | 50.9 | |||
Pneumonectomy | 68.7 | 62.5 | |||
Compartment of lymph node metastases | |||||
Hilar, yes/no | 55.2/58.9 | 0.709 | 53.8/47.7 | 0.417 | |
Interlobar, yes/no | 59.6/44.0 | 0.241 | 55.3/39.7 | 0.195 | |
Pulmonary, yes/no | 52.8/59.2 | 0.260 | 46.7/55.6 | 0.296 | |
Extranodal lymph node involvement | 0.570 | 0.399 | |||
Yes | 59.3 | 56.8 | |||
No | 54.6 | 49.0 | |||
Lymph node involvement due to | 0.350 | 0.880 | |||
Direct tumor involvement | 59.5 | 52.2 | |||
Metastatic lymph node involvement | 53.2 | 51.0 | |||
Number of lymph node metastases | 0.126 | 0.045 | |||
Single | 64.5 | 62.9 | |||
Multiple | 49.3 | 42.3 | |||
Central tumor location (<2 cm) | 0.170 | 0.386 | |||
Yes | 62.3 | 56.9 | |||
No | 50.3 | 47.1 | |||
T descriptor | 0.580 | 0.460 | |||
pT1 | 59.1 | 56.0 | |||
pT2 | 55.5 | 50.1 | |||
UICC stage | 0.051 | 0.011 | |||
IIA | 63.0 | 60.0 | |||
IIB | 38.9 | 31.1 | |||
Adjuvant chemotherapy | 0.560 | 0.639 | |||
Yes | 57.9 | 53.9 | |||
No | 55.2 | 50.3 |
UICC, Union for International Cancer Control.