Table 2.
Characteristic | VL ≥1000 copies/mL, n/N (%) | Unadjusted OR (95% CI) | P value | aOR | P value |
---|---|---|---|---|---|
Gender | |||||
male | 47/521 (9.0) | 1 | |||
female | 50/648 (7.7) | 0.84 (0.56–1.29) | 0.422 | 0.82 (0.53–1.25) | 0.350 |
a Age group (years) | |||||
<35 | 52/513 (10.1) | 1 | |||
≥35 | 45/656 (6.9) | 0.65 (0.43–0.99) | 0.045 | 0.64 (0.41–0.97) | 0.042 |
Education level | 0.056 | 0.043 | |||
never | 13/189 (6.9) | 1 | |||
primary | 72/907 (7.9) | 1.17 (0.63–2.15) | 0.620 | 1.08 (0.58–2.00) | 0.807 |
secondary/higher | 12/73 (16.4) | 2.66 (1.15–6.15) | 0.022 | 2.42 (1.04–5.64) | 0.041 |
b Marital status | |||||
married | 57/712 (8.0) | 1 | |||
not married | 40/457 (8.7) | 1.10 (0.72–1.68) | 0.651 | ||
a ART regimen | |||||
NVP versus EFV (NNRTIs) | |||||
NVP-based | 31/295 (10.5) | 1 | |||
EFV-based | 66/880 (7.5) | 0.70 (0.44–1.09) | 0.048 | 0.59 (0.34–0.91) | 0.020 |
TDF versus ZDV (NRTIs) | |||||
TDF + 3TC + EFV/NVP | 65/873 (7.4) | 1 | |||
ZDV + 3TC + EFV/NVP | 32/282 (11.3) | 1.59 (1.02–2.49) | 0.041 | 2.10 (1.29–3.46) | 0.003 |
Median months on ART | |||||
≤12 | 47/474 (9.9) | 1 | |||
≥24 | 50/694 (7.2) | 0.71 (0.47–1.07) | 0.113 | 0.61 (0.39–0.97) | 0.035 |
3TC, lamivudine; EFV, efavirenz; NVP, nevirapine; TDF, tenofovir; ZDV, zidovudine. Statistically significant P values are shown in bold.
We classified the ART regimen into two categories, i.e. an NNRTI component (nevirapine-based versus efavirenz-based) and the second category based on the NRTI component (tenofovir versus zidovudine). We report P values of other variables in the model where the NNRTI component was included, although the statistical significance of the listed variables was maintained in the model in which we included the NRTI component (logistic regression model results of other variables were excluded except for NRTI variables in this case).
Only variables with a P value of ≤0.15 and a priori confounders (gender and age) were included in multivariate regression models.
Not married means single, divorced or separated.