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. 2019 Jun 30;74(10):3021–3029. doi: 10.1093/jac/dkz261

Table 2.

Correlates of VF among fisherfolk on first-line ART in Uganda

Characteristic VL ≥1000 copies/mL, n/N (%) Unadjusted OR (95% CI) P value aOR P value
Gender
 male 47/521 (9.0) 1
 female 50/648 (7.7) 0.84 (0.56–1.29) 0.422 0.82 (0.53–1.25) 0.350
a Age group (years)
 <35 52/513 (10.1) 1
 ≥35 45/656 (6.9) 0.65 (0.43–0.99) 0.045 0.64 (0.41–0.97) 0.042
Education level 0.056 0.043
 never 13/189 (6.9) 1
 primary 72/907 (7.9) 1.17 (0.63–2.15) 0.620 1.08 (0.58–2.00) 0.807
 secondary/higher 12/73 (16.4) 2.66 (1.15–6.15) 0.022 2.42 (1.04–5.64) 0.041
b Marital status
 married 57/712 (8.0) 1
 not married 40/457 (8.7) 1.10 (0.72–1.68) 0.651
a ART regimen
 NVP versus EFV (NNRTIs)
  NVP-based 31/295 (10.5) 1
  EFV-based 66/880 (7.5) 0.70 (0.44–1.09) 0.048 0.59 (0.34–0.91) 0.020
 TDF versus ZDV (NRTIs)
  TDF + 3TC + EFV/NVP 65/873 (7.4) 1
  ZDV + 3TC + EFV/NVP 32/282 (11.3) 1.59 (1.02–2.49) 0.041 2.10 (1.29–3.46) 0.003
Median months on ART
 ≤12 47/474 (9.9) 1
 ≥24 50/694 (7.2) 0.71 (0.47–1.07) 0.113 0.61 (0.39–0.97) 0.035

3TC, lamivudine; EFV, efavirenz; NVP, nevirapine; TDF, tenofovir; ZDV, zidovudine. Statistically significant P values are shown in bold.

We classified the ART regimen into two categories, i.e. an NNRTI component (nevirapine-based versus efavirenz-based) and the second category based on the NRTI component (tenofovir versus zidovudine). We report P values of other variables in the model where the NNRTI component was included, although the statistical significance of the listed variables was maintained in the model in which we included the NRTI component (logistic regression model results of other variables were excluded except for NRTI variables in this case).

a

Only variables with a P value of ≤0.15 and a priori confounders (gender and age) were included in multivariate regression models.

b

Not married means single, divorced or separated.