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. 2019 Sep 13;9:871. doi: 10.3389/fonc.2019.00871

Table 2.

Correlation of Minimal Residual Disease status with Deletions and Duplications in individual genes/loci.

CNA in genes MRD − MRD+ Fisher's exact (p) FDR (p. adj.) CNA in Genes MRD − MRD+ Fisher's exact (p) FDR (p. adj.)
IKZF1 deletion 13 6 0.77 1 LEF1 gain 2 6 0.005* 0.08
IKZF wt 54 19 LEF1 wt 64 19
CDKN2A/B deletion 18 2 0.08 0.7 NR3C2 gain 3 6 0.010* 0.08
CDKN2A/B wt 48 22 NR3C2 wt 62 18
BTG1 Deletion 4 1 1 1 RUNX1 gain 14 12 0.015* 0.08
BTG1 wt 61 24 RUNX1 wt 50 11
EBF1 deletion 3 0 0.55 0.95 PAR1 gain 10 9 0.042* 0.17
EBF1 wt 58 25 PAR1 wt 56 16
PAX5 deletion 16 3 0.38 0.86 PHF6 gain 10 8 0.081 0.25
PAX5 wt 49 20 PHF6 wt 57 17
ETV6 deletion 13 4 0.77 1 CASP8AP2 gain 6 6 0.092 0.25
ETV6 wt 53 21 CASP8AP2 wt 57 19
Rb1 deletion 3 0 0.56 0.95 PTPN2 gain 2 3 0.122 0.28
Rb1 wt 64 25 PTPN2 wt 65 22
MLLT3 deletion 12 2 0.33 0.86 MYB gain 7 6 0.177 0.35
MLLT3 wt 54 23 MYB wt 58 19
MTAP deletion 16 2 0.14 0.79 PTEN gain 9 6 0.224 0.4
MTAP wt 50 23 PTEN wt 58 19
NF1+SUZ12 del. 0 2 0.06 0.7 TOX gain 5 4 0.261 0.42
NF1+SUZ12 wt 61 19 TOX wt 59 21
EPHA1 deletion 2 2 0.3 0.86 ADD3 gain 3 3 0.34 0.47
EPHA1 wt 64 23 ADD3 wt 63 22
EZH2 deletion 2 2 0.3 0.86 IGHM gain 10 6 0.35 0.47
EZH2 wt 64 23 IGHM wt 49 16
VPREB deletion 13 7 0.41 0.86 DMD gain 6 4 0.446 0.55
VPREB wt 53 18 DMD wt 61 20
CD200/BTLA deletion 4 1 1 1 PDGFRB gain 3 0 0.5 0.57
CD200/BTLA wt 62 23 PDGFRB wt 64 25
TBL1XR1 deletion 5 1 1 1 NR3C1 gain 4 0 0.57 0.61
TBL1XR1 wt 62 23 NR3C1 wt 62 24
IGHM deletion 8 3 1 1 LMO1 gain 4 2 0.668 0.67
IGHM wt 49 16 LMO1 wt 61 23
*

and bold p < 0.05 were considered statistically significant.

p values showing a trend of correlation are shown in bold.