Table 2.
CNA in genes | MRD − | MRD+ | Fisher's exact (p) | FDR (p. adj.) | CNA in Genes | MRD − | MRD+ | Fisher's exact (p) | FDR (p. adj.) |
---|---|---|---|---|---|---|---|---|---|
IKZF1 deletion | 13 | 6 | 0.77 | 1 | LEF1 gain | 2 | 6 | 0.005* | 0.08 |
IKZF wt | 54 | 19 | LEF1 wt | 64 | 19 | ||||
CDKN2A/B deletion | 18 | 2 | 0.08 | 0.7 | NR3C2 gain | 3 | 6 | 0.010* | 0.08 |
CDKN2A/B wt | 48 | 22 | NR3C2 wt | 62 | 18 | ||||
BTG1 Deletion | 4 | 1 | 1 | 1 | RUNX1 gain | 14 | 12 | 0.015* | 0.08 |
BTG1 wt | 61 | 24 | RUNX1 wt | 50 | 11 | ||||
EBF1 deletion | 3 | 0 | 0.55 | 0.95 | PAR1 gain | 10 | 9 | 0.042* | 0.17 |
EBF1 wt | 58 | 25 | PAR1 wt | 56 | 16 | ||||
PAX5 deletion | 16 | 3 | 0.38 | 0.86 | PHF6 gain | 10 | 8 | 0.081 | 0.25 |
PAX5 wt | 49 | 20 | PHF6 wt | 57 | 17 | ||||
ETV6 deletion | 13 | 4 | 0.77 | 1 | CASP8AP2 gain | 6 | 6 | 0.092 | 0.25 |
ETV6 wt | 53 | 21 | CASP8AP2 wt | 57 | 19 | ||||
Rb1 deletion | 3 | 0 | 0.56 | 0.95 | PTPN2 gain | 2 | 3 | 0.122 | 0.28 |
Rb1 wt | 64 | 25 | PTPN2 wt | 65 | 22 | ||||
MLLT3 deletion | 12 | 2 | 0.33 | 0.86 | MYB gain | 7 | 6 | 0.177 | 0.35 |
MLLT3 wt | 54 | 23 | MYB wt | 58 | 19 | ||||
MTAP deletion | 16 | 2 | 0.14 | 0.79 | PTEN gain | 9 | 6 | 0.224 | 0.4 |
MTAP wt | 50 | 23 | PTEN wt | 58 | 19 | ||||
NF1+SUZ12 del. | 0 | 2 | 0.06 | 0.7 | TOX gain | 5 | 4 | 0.261 | 0.42 |
NF1+SUZ12 wt | 61 | 19 | TOX wt | 59 | 21 | ||||
EPHA1 deletion | 2 | 2 | 0.3 | 0.86 | ADD3 gain | 3 | 3 | 0.34 | 0.47 |
EPHA1 wt | 64 | 23 | ADD3 wt | 63 | 22 | ||||
EZH2 deletion | 2 | 2 | 0.3 | 0.86 | IGHM gain | 10 | 6 | 0.35 | 0.47 |
EZH2 wt | 64 | 23 | IGHM wt | 49 | 16 | ||||
VPREB deletion | 13 | 7 | 0.41 | 0.86 | DMD gain | 6 | 4 | 0.446 | 0.55 |
VPREB wt | 53 | 18 | DMD wt | 61 | 20 | ||||
CD200/BTLA deletion | 4 | 1 | 1 | 1 | PDGFRB gain | 3 | 0 | 0.5 | 0.57 |
CD200/BTLA wt | 62 | 23 | PDGFRB wt | 64 | 25 | ||||
TBL1XR1 deletion | 5 | 1 | 1 | 1 | NR3C1 gain | 4 | 0 | 0.57 | 0.61 |
TBL1XR1 wt | 62 | 23 | NR3C1 wt | 62 | 24 | ||||
IGHM deletion | 8 | 3 | 1 | 1 | LMO1 gain | 4 | 2 | 0.668 | 0.67 |
IGHM wt | 49 | 16 | LMO1 wt | 61 | 23 |
and bold p < 0.05 were considered statistically significant.
p values showing a trend of correlation are shown in bold.