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. 2019 Sep 13;10:1030. doi: 10.3389/fphar.2019.01030

Figure 7.

Figure 7

Dioscin regulates P53-mediated apoptosis pathway in vivo and in vitro. (A B) Effects of dioscin on the expression levels of BAX and BCL-2 in AML-12 cells. (C D) Effects of dioscin on the expression levels of P53, BAX, BCL-2 in mice. All data are presented as the mean ± SD (n = 3 for in vitro test and n = 8 for in vivo test). *p < 0.05 and **p < 0.01 compared with the model group. # p < 0.05, ## p < 0.01 compared with the control group. AML-12, alpha mouse liver 12; BAX, BCL-2-associated X; P53, tumor suppressor P53.