Figure 4.

Atomic force microscopy (PeakForce Tapping mode) images of inorganic silica/halloysite imprints templated on HeLa cells: (A) topography image, (B) non-specific adhesion map; (C) scanning electron microscopy image of inorganic silica/halloysite imprints templated on HeLa cells; (D) EDX spectrum taken from the sample shown in (C), demonstrating the typical silica and halloysite elemental distribution; (E) optical and (F) confocal microscopy images demonstrating the recognition of HeLa cells with cell-templated imprints (cell nuclei stained with DAPI, imprints with rhodamine B in panel (F); (G) optical microscopy image of selective recognition of HeLa cells by the imprint in a mixture of human cells with yeast cells.