Figure 6.

EGb761 inhibited the hepatic metastases of orthotopic tumors in an orthotopic transplantation model. Orthotopic transplantation mice were randomly divided into 2 groups for treatment – intraperitoneal injection of EGb761 (40 mg/kg) or saline (0.9%) – twice a week. HE staining was used to evaluate liver histology in different groups. Hepatic metastases were found in the control group (A) but not in the EGb761 group (B). “T” means tumor. “N” means normal tissue. Representative images are presented.