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. 2019 Sep 13;10:2085. doi: 10.3389/fmicb.2019.02085

TABLE 2.

Protein-coding genes found as non-essential in PG45 but essential in JF4278.

Essential CDS in JF4278 (MBOVJF4278_) Product Non-essential PG45 homolog1 (MBOVPG45_) PG2 ortholog2 (MAG_) Gene persistence3 Essential UAB CTIP ortholog4 (MYPU_) Core mycoplasma genes5 (CEMyc_)
00029 tRNA modification GTPase MnmE 0060 0530 20 0130 0050
00034 50S ribosomal protein L34 0065 7500 20 1540 N/A
00088 Oligopeptide transport ATP-binding protein OppF 0116 1040 15 N/A N/A
00110 Transport system permease protein PotB 0135 1260 20 4240 0750
00180 Hypothetical protein 0662 N/A N/A N/A N/A
00300 SUA5-like translation suppressor 0534 4520 17 6130 N/A
00382 Potassium transporter trkA 0464 3750 17 1370 N/A
00448 Endonuclease MutS2 0404 3140 1 N/A N/A
00463 Hypothetical protein 0390 3010 7 7700 N/A
00529 Hypothetical protein 0349 4660 11 N/A N/A
00561 Putative endonuclease 4 0317 4990 20 6210∗ 01290
00655 S-adenosylmethionine synthase 0227 5800 20 7020 01380
00755 Modification methylase DpnIIB 0766 6680 4 N/A N/A
00792 Ribosome maturation factor RimP 0800 7000 7 N/A N/A
00833 Putative RNA pseudouridine synthase 0831 7190 11 N/A N/A
00841 Chaperone protein DnaJ 0839 7280 12 7330 01460
00846 Phenylalanine-tRNA ligase beta subunit 0845 7310 14 4860 N/A
00857 SsrA-binding protein 0855 7390 20 3520 0650
00865 Catabolite control protein A 0858 7400 5 N/A N/A

1Non-essential homolog in M. bovis PG45 (Sharma et al., 2014). 2M. agalactiae strain PG2 ortholog. 3Gene persistence out of 20 Mycoplasma spp. (Liu et al., 2012). 4Essential gene in M. pulmonis strain UAB CTIP (French et al., 2008). 5Core set of essential genes in Mycoplasma genomes (Lin and Zhang, 2011). ∗Non-essential gene in M. pulmonis strain UAB CTIP (Dybvig et al., 2010).