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. 2019 Sep 13;13:960. doi: 10.3389/fnins.2019.00960

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Copyright © 2019 Shan, Zhao, Qiu, Wu, Chen, Fang, Guo and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The subjects of response or remission at 8 weeks treatment in the guided group and the unguided group. Response to therapy was defined as the RR of HAMD-17 by ≥ 50%. Remission was defined as the final HAMD-17 score ≤ 7 at the end of the 8-week treatment. The two histogram bars on the left represent the treatment response of two groups and the two right represent treatment remission of two groups. P-values on the left and right represent the comparison of response rates and remission rates respectively, between two groups. P-values are derived using χ² tests. HAMD-17 = 17-item Hamilton depression scale; RR, reduction ratio.