Table 5.
Forty-four significantly differentially expressed osteoarthritis risk genes.
| ID | T | B | Fold change | Gene | P |
|---|---|---|---|---|---|
| ILMN_1659703 | −4.6029458 | 3.22309 | 0.87 | WWP2 | 9.31E−06 |
| ILMN_1721535 | 4.0329713 | 1.10042 | 1.26 | COG5 | 9.05E−05 |
| ILMN_1800049 | −3.68066 | −0.10141 | 0.96 | MAPT | 3.32E−04 |
| ILMN_1804895 | −3.4402192 | −0.86996 | 0.92 | LSMEM1 | 7.68E−04 |
| ILMN_1778886 | −3.397218 | −1.00284 | 0.92 | ZNF345 | 8.89E−04 |
| ILMN_1738239 | −3.3661954 | −1.09784 | 0.84 | RBM6 | 9.86E−04 |
| ILMN_1698621 | 3.1752911 | −1.66604 | 1.07 | COG5 | 1.84E−03 |
| ILMN_1768261 | −3.0820359 | −1.93322 | 0.95 | PRDM2 | 2.48E−03 |
| ILMN_1673708 | 2.9367424 | −2.33566 | 1.02 | HDAC9 | 3.88E−03 |
| ILMN_1776858 | −2.924587 | −2.36856 | 0.93 | DUS4L | 4.03E−03 |
| ILMN_1772218 | 2.8667893 | −2.52332 | 1.12 | HLA-DPA1 | 4.79E−03 |
| ILMN_1785402 | −2.7406448 | −2.85157 | 0.95 | LTBP1 | 6.94E−03 |
| ILMN_1790384 | −2.7296251 | −2.87962 | 0.96 | PRDM2 | 7.16E−03 |
| ILMN_1802973 | −2.7280423 | −2.88364 | 0.87 | ANAPC4 | 7.20E−03 |
| ILMN_1699469 | 2.6997749 | −2.95509 | 1.03 | KCNIP4 | 7.80E−03 |
| ILMN_1749026 | −2.6961724 | −2.96415 | 0.98 | LCT | 7.88E−03 |
| ILMN_1693559 | 2.678254 | −3.00904 | 1.02 | DOT1L | 8.29E−03 |
| ILMN_1690442 | −2.6764894 | −3.01345 | 0.97 | TMEM241 | 8.34E−03 |
| ILMN_2381121 | 2.6586005 | −3.05797 | 1.06 | UQCC1 | 8.77E−03 |
| ILMN_1682981 | −2.6104688 | −3.17642 | 0.95 | SMG6 | 1.00E−02 |
| ILMN_1753353 | 2.5464314 | −3.33099 | 1.07 | SLBP | 1.20E−02 |
| ILMN_1823056 | −2.4053844 | −3.65907 | 0.98 | CCDC33 | 1.75E−02 |
| ILMN_1716651 | 2.4049149 | −3.66013 | 1.07 | RUNX2 | 1.75E−02 |
| ILMN_2408885 | 2.3961067 | −3.68005 | 1.03 | HDAC9 | 1.79E−02 |
| ILMN_1701361 | −2.3821458 | −3.71148 | 0.98 | LURAP1L | 1.86E−02 |
| ILMN_1754121 | 2.3523213 | −3.77806 | 1.09 | CSK | 2.01E−02 |
| ILMN_1693427 | −2.3253143 | −3.83768 | 0.98 | GLIS3 | 2.15E−02 |
| ILMN_1747386 | −2.3074266 | −3.87682 | 0.98 | GLIS3 | 2.25E−02 |
| ILMN_1717780 | 2.2917001 | −3.911 | 1.02 | PLEC | 2.34E−02 |
| ILMN_1771987 | 2.2874158 | −3.92028 | 1.12 | SLC44A2 | 2.37E−02 |
| ILMN_2145670 | 2.2761251 | −3.94464 | 1.03 | TNC | 2.44E−02 |
| ILMN_1784287 | 2.2239902 | −4.05569 | 1.17 | TGFBR3 | 2.78E−02 |
| ILMN_2129668 | −2.200499 | −4.10495 | 0.98 | TGFB1 | 2.94E−02 |
| ILMN_1780291 | −2.1782335 | −4.15119 | 0.95 | NFAT5 | 3.11E−02 |
| ILMN_1882354 | 2.1649163 | −4.17863 | 1.15 | FAM53A | 3.21E−02 |
| ILMN_1680399 | −2.1603694 | −4.18797 | 0.97 | KAZN | 3.25E−02 |
| ILMN_1726387 | −2.1502554 | −4.20866 | 0.97 | NF1 | 3.33E−02 |
| ILMN_1654421 | −2.129798 | −4.25025 | 0.94 | MPHOSPH9 | 3.50E−02 |
| ILMN_1724734 | 2.1181634 | −4.27374 | 1.03 | UQCC1 | 3.59E−02 |
| ILMN_2381559 | 2.0754774 | −4.35887 | 1.02 | ASTN2 | 3.98E−02 |
| ILMN_1673620 | −2.0711976 | −4.36732 | 0.97 | KIF26B | 4.02E−02 |
| ILMN_1871893 | −2.0480746 | −4.41267 | 0.98 | LINC01507 | 4.24E−02 |
| ILMN_2046073 | 2.0412532 | −4.42596 | 1.02 | LCT | 4.31E−02 |
| ILMN_1813277 | 2.0065873 | −4.49284 | 1.11 | SUPT3H | 4.67E−02 |
T, Moderated t-statistic; B, B-statistic or log-odds that the gene is differentially expressed; F, Moderated F-statistic combines the t-statistics for all the pair-wise comparisons into an overall test of significance for that gene.