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. 2019 Sep 20;16(9):e1002902. doi: 10.1371/journal.pmed.1002902

Table 1. Summary of characteristics of growth charts explored.

Characteristics Population Customised Intergrowth
Population used for development Swedish population (internally developed using Swedish Medical Birth Registry population available to this study, n = 233,379) Combination of registries and datasets for multiple countries (www.gestation.net) Pooled data from single-centre cohorts in eight countries (n = 20,486)
Estimated fetal weight versus birth weight Birth-weight chart Term optimal weight was developed using birth weight. In the preterm period, fetal weight has been estimated using a proportionality formula based on the Hadlock’s fetal weight equation Birth-weight chart
Descriptive versus prescriptivea Retrospective development of a descriptive chart Retrospective development of a prescriptive chart Prospective development of a prescriptive chart
Adjustment/covariates Gestational age and infant sex Maternal ethnicity, height and weight, parity, gestational age, and infant sex Gestational age and infant sex
Underlying principle Infants in a given population should have a similar growth potential Infant growth potential is physiologically influenced by maternal and fetal factors Infants worldwide should have a similar growth potential

aDescriptive charts are also known as ‘references’ and describe the estimated fetal weight or birth weight in the whole sample, including women with comorbidities such as preeclampsia or gestational diabetes. Prescriptive charts are also known as standards and aim to report growth in presumably healthy individuals, usually excluding the effect of comorbidities, smoking, and socioeconomic status (amongst other factors). The factors used to presume a healthy population may vary between charts.