Table 4. Logistic regression with generalized estimating equations analyses (GEE) of predictors of disease relapse in pregnancy and post-partum period among SLE patients.
Clinical variables | B Coefficient | OR (95% C.I) | P |
---|---|---|---|
Relapse in pregnancy | |||
Active disease at conception | 1.54 | 4.66 (1.03–21.38) | 0.04 |
Chinese | 0.61 | 1.84 (0.63–5.37) | 0.27 |
Musculoskeletal | -0.66 | 0.82 (0.22–1.29) | 0.14 |
Malay | -0.51 | 0.60 (0.25–1.47) | 0.27 |
Active LN at conception | -0.43 | 0.65 (0.15–2.69) | 0.55 |
Active haematology at conception | -0.26 | 0.77 (0.17–3.51) | 0.73 |
Duration of remission | 0.02 | 1.11 (0.99–1.04) | 0.17 |
Hydroxychloroquine in pregnancy | -0.54 | 0.58 (0.31–1.11) | 0.10 |
Relapse post-partum | |||
Age at conception | 0.13 | 1.14 (1.04–1.26) | 0.01 |
Active disease at conception | 0.91 | 2.48 (1.08–5.69) | 0.03 |
Malay | 1.35 | 3.87 (1.29–11.51) | 0.02 |
HCQ in pregnancy | -0.72 | 0.49 (0.13–1.82) | 0.28 |
HCQ post partum | -0.54 | 0.59 (0.19–1.83) | 0.35 |
Duration of remission | 0.01 | 1.01 (0.98–1.05) | 0.66 |
HCQ = hydroxychloroquin