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. Author manuscript; available in PMC: 2019 Sep 20.
Published in final edited form as: Methods Mol Biol. 2019;1899:211–227. doi: 10.1007/978-1-4939-8938-6_15

Table 2.

Histology scoring of EAU in the mouse

Grade Criteria for histopathology
0 Normal retina structure
0.5/trace Mild inflammatory cell infiltration. No tissue damage
1 Infiltration; retinal folds and focal retinal detachments; few small granulomas in choroid and retina, perivasculitis
2 Moderate infiltration; retinal folds, detachments and focal photoreceptor cell damage; small to medium sized granulomas, perivasculitis and vasculitis
3 Medium to heavy infiltration; extensive retinal folding with detachments, moderate photoreceptor cell damage; medium sized granulomatous lesions; subretinal neovascularization
4 Heavy infiltration; diffuse retinal detachment with serous exudate and subretinal bleeding; extensive photoreceptor cell damage; large granulomatous lesions; subretinal neovascularization