Table 3.

Summary of Results for All Outcome Measures.

Outcome Measure		Condition			Time		Condition × Time
	F	p	${\eta }_p^2$	F	p	${\eta }_p^2$	F	p	${\eta }_p^2$
MCP	9.75	< .001	.30	1.96	ns	.08	0.74	ns	.03
Plasma Nicotine	21.51	< .001	.48	32.92	< .001	.59	10.85	< .001	.32
HR	6.95	< .001	.23	51.02	< .001	.69	12.36	< .001	.35
Systolic BP	8.44	< .001	.27	2.44	ns	.10	1.26	ns	.05
Diastolic BP	8.87	< .001	.28	6.42	< .001	.22	2.41	< .05	.10
Subjective Measures
Hughes-Hatsukamia
Anxious	1.55	ns	.06	8.20	< .001	.26	2.90	< .05	.09
Craving	11.02	< .001	.32	12.40	< .001	.35	6.80	< .001	.23
Depression	0.91	ns	.04	0.47	ns	.02	1.59	ns	.06
Difficulty concentrating	1.88	ns	.08	2.34	ns	.09	0.73	ns	.03
Drowsy	1.18	ns	.05	1.95	ns	.08	1.87	ns	.08
Hunger	1.70	ns	.07	5.83	< .01	.20	1.13	ns	.05
Impatient	2.00	ns	.08	6.39	< .001	.22	1.91	< .05	.08
Irritable	0.48	ns	.02	6.21	< .01	.21	1.12	ns	.05
Restless	2.84	ns	.11	2.97	< .05*	.11	1.39	ns	.06
Sweets	0.90	ns	.04	1.30	ns	.05	1.28	ns	.05
Urge	7.51	< .001	.25	17.98	< .001	.44	3.37	< .01	.13
Direct effects of nicotine b
Confused	0.18	ns	.01	0.83	ns	.04	1.18	ns	.06
Dizzy	2.65	ns	.12	3.41	< .05*	.15	2.15	ns	.10
Headache	0.41	ns	.02	0.73	ns	.04	1.17	ns	.06
Heart pound	1.05	ns	.05	1.84	ns	.08	1.19	ns	.06
Light headed	5.62	< .01	.22	5.14	< .01	.21	2.61	< .05	.12
Nausea	1.34	ns	.06	0.12	ns	.01	1.19	ns	.06
Nervous	0.19	ns	.01	2.01	ns	.09	0.80	ns	.04
Salivate	0.13	ns	.01	1.98	ns	.09	0.48	ns	.02
Sweaty	0.22	ns	.01	5.44	< .01	.21	0.77	ns	.04
Weak	1.02	ns	.05	0.34	.76	.02	0.63	ns	.03
Direct effects of product use c
Awake	15.45	< .001	.42	6.71	< .01	.24	1.49	ns	.07
Calm	14.86	< .001	.41	11.43	< .001	.35	2.26	< .05	.10
Concentrate	11.49	< .001	.35	0.07	ns	.00	0.54	ns	.03
Dizzy	8.16	< .001	.28	2.76	ns	.12	1.74	ns	.08
Pleasant	34.26	< .001	.62	4.59	< .05	.18	1.81	ns	.08
Reduced hunger	9.54	< .001	.31	1.20	ns	.05	0.87	ns	.04
Right now	0.59	ns	.03	5.70	< .01	.21	1.81	ns	.08
Satisfy	44.20	< .001	.68	2.54	ns	.11	2.11	ns	.09
Sick	1.05	ns	.05	0.23	ns	.01	0.64	ns	.03
Taste good	40.48	< .001	.66	3.87	< .05	.16	1.96	ns	.09
Tiffany-Drobesd
Factor 1	9.18	< .001	.32	16.90	< .001	.46	8.71	< .001	.30
Factor 2	2.25	ns	.10	6.31	< .05	.24	4.40	< .01	.18

Note.

^aHughes and Hatsukami Tobacco Withdrawal Scale,

^bDirect Effects of Nicotine Use,

^cDirect Effects of Product Use,

^dTiffany-Drobes Questionnaire of Smoking Urges Brief.

^(*)Asterisk denotes items that did not have a statistical difference between condition or time points with follow up post-hoc tests.