Symmetry of limb movement (suspended by tail) |
All limbs extended symmetrically |
Limbs on one side were outstretched less than the other |
Unable to hang |
Yes |
Lateral turning |
Responded to stimulus on both sides |
Responded to stimulus on one side only |
Did not respond to stimulus on either side |
Yes |
Climbing (45° angle on gripping surface) |
Climbed to the top easily with a firm grip |
Asymmetric or paired climbing or slipped |
Failed to climb or fell off apparatus |
No |
Spontaneous activity during 5 min in typical cage |
Moved around, explored environment and reached the upper rim ≥3 sides of cage |
Moved hesitatingly around, explored, and reached the upper rim < 3 sides of cage |
Severely affected rat did not rise-up at all, and barely moved in the cage |
No |
Forelimb outstretching (suspended by tail, forepaws to table) |
Both forelimbs outstretched, walking symmetrically on forepaws |
Impaired forepaw walking with asymmetric outstretch |
Limbs on one side showed minimal movement |
No |
Axial sensation (mild stimulus to the trunk from behind) |
Equally startled to the stimulus on both sides of trunk |
Reacted more slowly on one side compared to other |
Did not respond to stimulus on one side |
No |
Vibrissae proprioception (gentle touch from behind) |
Equally turned head to cotton-wisp on both sides |
Reacted to one side only |
Did not respond to stimulus on either side |
No |