Table 3: R² values for correlations between HO-1 expression and lesion volumes.

Table showing the different R² values obtained for the correlation tests between the different lesion volume components (total, edema, and hemorrhage) and the HO-1 expression (integrated density and staining area). The P value of the linear regression associated with each correlation is noted under the R² value.

	All groups		NON-treated animals		OPN-treated animals
	Integrated density	Staining area	Integrated density	Staining area	Integrated density	Staining area
Total lesion volume	R2=0.7295 P<0.0001	R2=0.8537 P<0.0001	R2=0.9238 P<0.0001	R2=0.8726 P<0.0001	R2=0.6912 P=0.0029	R2=0.8253 P=0.0003
Edema	R2=0.7331 P<0.0001	R2=0.8533 P<0.0001	R2=0.9433 P<0.0001	R2=0.8751 P<0.0001	R2=0.6937 P=0.0028	R2=0.8211 P=0.0003
Hemorrhage	R2=0.4459 P=0.0013	R2=0.5583 P=0.0002	R2=0.4065 P=0.0464	R2=0.5081 P=0.0207	R2=0.4941 P=0.0233	R2=0.6419 P=0.0055

^****P<0.0001

^***P<0.001

^**P<0.01

^*P<0.05