Table 2:
Adjusted associations between disease activity and other factors and discontinuation of alcohol use among active drinkers.
| Odds of Discontinuation Among Active Drinkers (N=7,817; Obs=51,073) |
Odds of Initiation Among Abstainers (N=7,768; Obs=48,413) |
|||
|---|---|---|---|---|
| OR (95% CI) | p | OR (95% CI) | p | |
| Age <50 | Reference | Reference | ||
| Age 50–60 | 1.01 (0.90, 1.12) | 0.90 | 0.85 (0.77, 0.94) | 0.002 |
| Age 60–70 | 1.04 (0.93, 1.16) | 0.13 | 0.76 (0.68, 0.85) | <0.001 |
| Age 70–80 | 1.12 (0.98, 1.27) | 0.002 | 0.66 (0.58, 0.74) | <0.001 |
| Age >80 | 1.27 (1.08, 1.51) | 0.005 | 0.72 (0.60, 0.85) | <0.001 |
| Male | 0.72 (0.64, 0.81) | <0.001 | 1.18 (1.04, 1.34) | 0.01 |
| White | 0.73 (0.62, 0.87) | <0.001 | 1.10 0.92, 1.31) | 0.30 |
| BMI | ||||
| Low | 1.03 (0.71, 1.50) | 0.86 | 0.94 (0.64, 1.36) | 0.73 |
| Normal | Reference | reference | ||
| Overweight | 1.04 (0.93, 1.17) | 0.47 | 0.99 (0.88, 1.11) | 0.84 |
| Obese | 1.37 (1.22, 1.54) | <0.001 | 1.05 (0.94, 1.18) | 0.38 |
| Methotrexate | 1.05 (0.97, 1.13) | 0.21 | 0.90 (0.84, 0.97) | 0.004 |
| Prednisone | 1.06 (0.98, 1.14) | 0.16 | 0.95 (0.88, 1.02) | 0.16 |
| Any Biologic | 0.94 (0.87, 1.01) | 0.08 | 1.06 (0.99, 1.14) | 0.12 |
| PAS-II | ||||
| Remission | Reference | Reference | ||
| Low | 1.07 (1.00, 1.15) | 0.06 | 0.97 (0.91, 1.04) | 0.43 |
| Mod-High | 1.22 (0.90, 1.66) | 0.19 | 0.95 (0.77, 1.18) | 0.66 |
| Work Disability | 1.18 (1.06, 1.32) | 0.003 | 0.91 (0.83, 1.00) | 0.001 |
| RDCI | 1.02 (1.00, 1.04) | 0.02 | -- | -- |
| Liver Disease | 1.23 (0.99, 1.53) | 0.07 | -- | -- |
| Heart Disease | -- | -- | 0.90 (0.81, 0.99) | 0.06 |
| Diabetes | -- | -- | 0.83 (0.74, 0.93) | 0.002 |
| SF-36 PCS | 0.99 (0.98, 0.99) | <0.001 | 1.01 (1.01, 1.01) | <0.001 |
| SF-36 MCS | 0.99 (0.99,1.00) | 0.001 | -- | -- |
| Education ≥16 yrs | 0.84 (0.76, 0.93) | 0.001 | 1.19 (1.07, 1.31) | 0.001 |
| Income (Ref 0–25K) | -- | -- | ||
| 35–55K | 0.84 (0.77, 0.92) | <0.001 | 1.16 (1.08, 1.26) | <0.001 |
| 65–150K | 0.72 (0.65, 0.79) | <0.001 | 1.37 (1.24, 1.51) | <0.001 |
Also tested but not associated and not included in final models: Odds of discontinuation: disease duration, smoking, marital status, depression, psychiatric disease, malignancy, heart disorders, lung disease, and gastrointestinal disorders. Odds of initiation: disease duration, smoking, marital status, health satisfaction, depression, psychiatric disease, malignancy, lung disease, liver disease, and gastrointestinal disorders.
Abbreviations: Obs=Observations; OR= Odds Ratio; CI= Confidence Interval; BMI= Body Mass Index; PAS-II= Patient Activity Scale-II; RDCI= Rheumatic Disease Comorbidity Index; PCS= Physical Component Summary; MCS= Mental Component Summary