Fig. 3.

Functional pathways influenced by NDRG1, NDRG2, NDRG3, and NDRG4. a Distinct functional pathways for NDRG1, NDRG2, and NDRG4. b Shared functional pathways induced by ischemia and stress involving more than one NDRG family member. LDL, low-density lipoprotein; Olig2, oligodendrocyte lineage transcription factor 2; PRA1, Prenylated Rab Acceptor 1; BDNF, brain-derived neurotrophic factor; AP-1, activator protein 1; Snap25, synaptosomal-associated protein 25; SGK1, serum/glucocorticoid-regulated kinase 1; OL, oligodendrocyte; GLAST, glutamate transporter glutamate aspartate transporter; GLT-1, glutamate transporter 1