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. 2019 Sep 20;10(10):702. doi: 10.1038/s41419-019-1870-0

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — Cell viability as a function of PTX concentration of: a APT-NPs entrapping PTX (2.5:1 molar ratio) were added to A549 target cells and to BEAS2B, HeLa, CaCo-2, FSE, and HEK-293 cells; b APT-NPs entrapping PTX (2.5:1 molar ratio) added to A549 target cells vs. competitive binding conditions using a 100-fold excess of free S15-APTs, co-incubated with APT-NPs entrapping PTX. Values presented are means ± SE. Sigmoidal model curve were fitted using Eq. (3); c IC₅₀ values derived from the fitted dose-response curves; P-values obtained were <0.01 for BEAS2B and HeLa cells, <0.001 for CaCo2 and HEK-293 cells, and <0.0001 for FSE cells. (Symbols marked on the bars are only for identification).