Table 2.
Baseline characteristics and outcomes by profiles on day 1.
| Variables | Total (n = 1352) | Profile 1 (n = 175) | Profile 2 (n = 208) | Profile 3 (n = 969) | p |
|---|---|---|---|---|---|
| Age, years (IQR) | 69 (58,80) | 69 (55,82) | 69 (56,79) | 69 (59,80) | 0.466 |
| Gender, Male (%) | 816 (60) | 112 (64) | 119 (57) | 585 (60) | 0.400 |
| Ethnicity, n (%) | 0.047 | ||||
| ASIAN | 34 (3) | 9 (5) | 8 (4) | 17 (2) | |
| BLACK | 114 (8) | 14 (8) | 24 (12) | 76 (8) | |
| HISPANIC | 40 (3) | 9 (5) | 4 (2) | 27 (3) | |
| UNKNOWN | 220 (16) | 27 (15) | 36 (17) | 157 (16) | |
| WHITE | 944 (70) | 116 (66) | 136 (65) | 692 (71) | |
| Admission period, n (%) | <0.001 | ||||
| Before 2008 | 763 (56) | 69 (39) | 119 (57) | 575 (59) | |
| 2008 to 2012 | 589 (44) | 106 (61) | 89 (42) | 394 (41) | |
| GCS, median (IQR) | 15 (14,15) | 3 (3,7) | 15 (15,15) | 15 (15,15) | <0.001 |
| SOFA, median (IQR) | 6 (3,9) | 10 (7,12) | 10 (8,12) | 5 (3,7) | <0.001 |
| Mean MBP, median (IQR) | 76 (69,83) | 78 (70,87) | 72 (66,79) | 76 (69,83) | <0.001 |
| Minimum MBP, median (IQR) | 54 (44,62) | 53 (42,62) | 42.17 (28,53) | 56 (48,63) | <0.001 |
| Type of care unit, n (%) | <0.001 | ||||
| CCU | 422 (31) | 55 (31) | 34 (16) | 333 (34) | |
| CSRU | 219 (16) | 21 (12) | 44 (21) | 154 (16) | |
| MICU | 440 (33) | 68 (39) | 77 (37) | 295 (30) | |
| SICU | 143 (11) | 18 (10) | 27 (13) | 98 (10) | |
| TSICU | 128 (9) | 13 (7) | 26 (12) | 89 (9) | |
| Use of vasoactive agents | |||||
| Dopamine, n (%) | 272 (20) | 33 (19) | 75 (36) | 164 (17) | <0.001 |
| Epinephrine, n (%) | 128 (9) | 13 (7) | 63 (30) | 52 (5) | <0.001 |
| Norepinephrine, n (%) | 442 (33) | 67 (38) | 147 (71) | 228 (24) | <0.001 |
| Dobutamine, n (%) | 51 (4) | 2 (1) | 15 (7) | 34 (4) | 0.006 |
| Clinical outcomes | |||||
| Hospital LOS, days (IQR) | 8 (3,17) | 7 (2,18) | 4 (1,11) | 9 (4,17) | <0.001 |
| ICU LOS, days (IQR) | 4 (2,8) | 4 (1,10) | 2 (1,7) | 4 (2,8) | <0.001 |
| Hospital mortality, n (%) | 732 (54) | 110 (63) | 159 (76) | 463 (48) | <0.001 |
Abbreviations: ICU: intensive care unit; LOS: length of stay; UO: urine output; GCS: Glasgow coma scale; BP: blood pressure. SOFA: sequential organ failure assessment; CCU: coronary care unit; CSRU: cardiac surgery recovery unit; MICU: medical ICU; SICU: surgical ICU; TSICU: Trauma-Surgical ICU; MBP: mean arterial blood pressure.