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. 2019 Sep 20;9:13616. doi: 10.1038/s41598-019-49897-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Prediction of changed KEGG pathways using PICRUSt analysis. Selected pathways found to be significantly different among the different animal groups are depicted based on their relation to infection diseases (A), metabolic pathways (B) and immune response (C). Dot plots on the right show the differences in mean proportions between the two indicated groups using P values. All KEGG pathways that were significantly changed are detailed in Supplementary Table S6.