Table 4.

Parameters for Time to Recovery.

Definition of Time to Recovery (TTR)a First day meeting organ failure recovery criteria in all systems listed below, without any subsequent days with further organ system failure.

Cardiovascular recovery Mean arterial pressure >60 mmHg and no inotropic/vasopressor support (dopamine, dobutamine, epinephrine, norepinephrine, phenylephrine or vasopressin).

Hematologic recovery Platelet count >120,000/µL

Hepatic recovery Serum bilirubin <3 mg/dL

Renal recovery No dialysis and creatinine <1.3 mg/dL

Respiratory recovery No mechanical ventilation or PaO2/FiO2 > 300

^aA surviving patient who did not recover by day 28 or died prior to day 28 was assigned a TTR value of 30 days. Parameters used to define TTR were established by Cuschieri et al.¹⁹.