Table 1.
Demographic and clinical characteristics of patient subgroups and control group.
| Variable | Subgroup1 | Subgroup2 | Subgroup3 | Healthy controls |
|---|---|---|---|---|
| (n = 30) | (n = 50) | (n = 36) | (n = 118) | |
| Demographic characteristic | ||||
| Age, mean (SD) | 23.80 (7.25) | 27.22 (7.80) | 26.56 (6.34) | 26.01 (7.24) |
| Sex, male/female | 11/19 | 15/35 | 18/18 | 47/71 |
| Education years, mean (SD) | 13.63 (2.65) | 12.70 (3.33) b * | 14.47 (2.90) | 14.12 (3.20) |
| Clinical characteristics | ||||
| Total illness duration, months | 25.00 (33.23) | 32.93 (59.28) | 23.85 (42.06) | NA |
| Presence of suicidal thoughts, yes/no | 15/15 | 27/23 | 22/14 | NA |
| Presence of suicidal behavior, yes/no | 6/24 | 5/45 | 2/34 | NA |
| With/without family history | 5/25 | 5/45 | 2/34 | NA |
| First episode, yes/no | 18/12 | 30/20 | 23/13 | NA |
| No medication | 24 | 39 | 22 | NA |
| Antidepressants (taken at least 3 months ago) | ||||
| SSRI/SNRI/NaSSAs | 5/1/0 | 4/5/2 | 9/4/1 | NA |
| HAM-D, mean (SD) | 23.90 (4.79) | 21.56 (4.39) | 22.47 (4.01) | NA |
| HAM-A, mean (SD) | 15.46 (7.70) | 16.65 (7.10) | 14.62 (5.78) | NA |
NA, not available; HAM-D, Hamilton Rating Scale for Depression; HAM-A, Hamilton Rating Scale for Anxiety; SSRIs, selective serotonin reuptake inhibitors; SNRIs, serotonin–norepinephrine reuptake inhibitors; NaSSAs, noradrenergic and specific serotonergic antidepressants.
b*Subgroup 2 compared to healthy controls, P < 0.05.