Table 2.
Comparison of neurocognitive test results between controls and patient subgroups.
| Subgroup1 | Subgroup2 | Subgroup3 | HC | |
|---|---|---|---|---|
| IQ | ||||
| Verbal IQ | 106.77 (13.73) | 107.56 (15.29) | 106.35 (15.96) | 111.97 (15.69) |
| Performance IQ | 103.81 (13.89) | 102.51 (15.11) | 102.83 (12.54) | 109.43 (14.08) |
| Full scale IQ | 106.04 (12.94) | 105.83 (14.66) | 105.38 (14.39) | 111.99 (14.96) |
| RVP | ||||
| RVP_TH | 15.93 (6.38) | 16.04 (6.47) | 16.50 (5.85) | 17.16 (6.66) |
| RVP_TM | 9.25 (5.31) | 8.92 (5.20) | 10.50 (5.85) | 8.54 (5.68) |
| RVP_TFA | 4.53 (5.97)a* | 2.22 (2.55) | 1.53 (2.66) | 2.28 (3.92) |
| RVP_TCR | 228.64 (65.83) | 229.88 (68.66) | 249.50 (13.06) | 238.25 (57.95) |
| RVP_ML | 396.90 (176.63) | 413.85 (173.16) | 419.60 (97.53) | 397.47 (149.58) |
| DMS | ||||
| DMS_MCL | 3302.46 (862.46) | 3806.51 (1037.83) | 3660.62 (1308.04) | 3566.87 (895.59) |
| DMS_MCLA | 3417.44 (917.36) | 4012.14 (1243.01) | 3778.39 (1344.42) | 3774.10 (1014.52) |
| DMS_MCLS | 2990.39 (998.33) | 3322.36 (1295.71) | 3338.51 (1457.27) | 3010.15 (809.73) |
| DMS_TC | 33.32 (4.47)a* | 33.86 (4.36)b* | 34.81 (3.51) | 35.56 (3.35) |
| DMS_TCA | 23.68 (4.35)a** | 24.14 (4.01)b** | 25.22 (3.50) | 25.93 (3.07) |
| DMS_TCS | 9.64 (0.62) | 9.71 (0.61) | 9.59 (0.56) | 9.63 (0.66) |
| DMS_PEGC | 0.18 (0.12)a** | 0.16 (0.12)b** | 0.14 (0.11) | 0.11 (0.08) |
IQ, intelligence quotient; RVP, rapid visual information processing; DMS, delayed matching to sample; RVP_TFA, total false alarms; DMS_TC, total correct; DMS_TCA, total correct in all delays, DMS_PEGC, probability error given correct. Age, sex and educational level were controlled as covariates in the comparison between each subgroup versus the healthy control group (HC). Details of cognitive variables are described in Table S1.
a*P < 0.05, a*P < 0.01, subgroup 1 compared to HC, b*P < 0.05, b**P < 0.01, subgroup 2 compared to HC.