Fig. 3.

Structural basis for CaMKIIβ in bundling actin filaments. (A) Actin network produced in simulations by docking multiple actin filaments onto the structure in Fig. 2. Multiple actin strands can either align in parallel (yellow arrow) or form branched structures (blue arrow). (B) EM of negative stained CaMKII/actin rafts formed on a lipid monolayer. Actin filaments are arranged either in parallel (yellow circle) or branched (blue circle). For both simulations and experiments, the spacing between 2 adjacent CaMKII particles in the complexes is nearly fixed at 36 nm (red arrow).