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. Author manuscript; available in PMC: 2019 Sep 21.
Published in final edited form as: Curr Protoc Bioinformatics. 2018 Jun 5;62(1):e51. doi: 10.1002/cpbi.51

Table 12.5.1.

Annotation features found in Rfam Seed alignments

Field name Field tag Description
Accession number AC Stable accession number for each Rfam family. It is of the form RFxxxxx, where x is a digit.
Identifier ID Short and meaningful name for the family. It is not necessarily stable between releases.
Description DE A one-line description of the family.
Author AU Author of the entry
Seed source SE Source of the Seed alignment. May be author, PubMed ID, literature reference, or alignment method.
Secondary structure SS Source of the secondary structure mark-up. May be Predicted specifying the software used or Published showing the PubMed ID of the publication where the structure was obtained.
Gathering cutoff GA Bit score cutoff chosen to determine whether a match is a real member of the family.
Trusted cutoff TC Bit score of the lowest scoring match above the GA threshold.
Noise cutoff NC Bit score of the highest scoring match below the GA threshold.
Type TP RNA type (controlled vocabulary) must be one of the following:
 - Gene
  - antisense
  - antitoxin
  - CRISPR
  - microRNA
  - lncRNA
  - rRNA
  - ribozyme
  - sRNA
  - tRNA
  - snRNA
   -snoRNA
    - CD-box
    - HACA-box
    - scaRNA
   - splicing
 - Intron
 - Cis-regulatory element
  - IRES
  - frameshift element
  - leader
  - riboswitch
  - thermoregulator.
Build method BM Infernal command line parameters used to construct the family.
Database cross references DR GO: Gene Ontology terms
SO: Sequence Ontology terms
Optional:
miRBase identifier, snOPY identifier, database URL, or other cross reference.
Comment CC Free text comment.
WK Link to a Wikipedia article describing the family.
Sequence count SQ Number of sequences in the alignment.
CL Rfam clan (if a family is a member of a clan).

The full and up-to-date list is available in the USERMAN file from the Rfam FTP archive (see Internet Resources).