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CD spectra of pure tau (10 μM) (a), a mixture of tau (10 μM) and α-synuclein monomer (1 μM) (b), and a mixture of tau (10 μM) and α-synuclein filaments (1 μM, monomer concentration) (c) acquired at different incubation times. The CD signal of the mixtures decreased due to the precipitation of the protein aggregates.
