Figure 4.

Tropisetron did not affect locomotor activity or the motivation to seek natural reward and locomotor activity. (A) The number of nose-pokes for sweetened water and sweetened water intake after systemic tropisetron was the same as without tropisetron. (B) No difference in locomotor activity was measured between tropisetron- (n = 6) and saline-treated (n = 7) groups. Tropisetron or saline was administered 5 minutes before placing the animal into an open field chamber and locomotor activity was monitored. Data are represented as the mean values ± SEM.