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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Environ Int. 2019 Aug 29;132:105113. doi: 10.1016/j.envint.2019.105113

Table 2.

Baseline characteristics of participants according to quintiles of high- and low-pesticide-residue fruit and vegetable intake.

Quintile of High-Pesticide-Residue Fruit and
Vegetable Intake
Quintile of Low-Pesticide-Residue Fruit and
Vegetable Intake
Characteristics Quintile 1 Quintile 3 Quintile 5 Quintile 1 Quintile 3 Quintile 5
Nurses’ Health Study (1998)
Number of participants 13,305 13,199 13,115 13,150 13,153 13,127
High-pesticide-residue FVs (servings/d) 0.5(0.2) 1.3(0.1) 3.1(1.1) 0.9(0.7) 1.5(0.8) 2.3(1.2)
Low-pesticide-residue FVs (servings/d) 1.4(0.9) 2.2(1.0) 3.1(1.4) 0.8(0.3) 2.0(0.2) 4.1(1.1)
Total FVs (servings/d) 2.5(1.2) 4.5(1.3) 7.6(2.3) 2.4(1.1) 4.5(1.1) 7.7(2.2)
Age (y) 63.5(7.3) 63.6(7.0) 63.5(6.8) 63.7(7.3) 63.4(7.0) 63.4(6.8)
BMI (kg/m2) 26.8(5.5) 26.7(5.2) 26.2(5.1) 26.8(5.4) 26.6(5.2) 26.3(5.2)
White (%) 97.3 97.7 97.4 97.1 97.7 97.3
Physical activity (MET/wk) 18.0(78.5) 22.5(75.2) 28.7(69.6) 19.2(78.7) 22.0(71.7) 27.2(69.0)
Family history of diabetes (%) 28.0 27.7 28.7 28.8 29.0 27.6
Family history of MI (%) 20.0 19.9 20.9 20.3 20.1 20.4
Current smoker (%) 17.9 9.6 5.5 15.7 9.3 7.7
Premenopausal (%) 6.1 6.8 6.1 6.3 6.5 6.1
Current menopausal users (%) 43.8 47.6 48.5 45.2 48.3 48.0
Baseline hypertension (%) 42.3 41.8 40.0 40.7 41.6 42.7
Baseline hypercholesterolemia (%) 55.8 55.8 54.0 56.1 56.1 54.8
Baseline diabetes (%) 6.6 6.7 6.7 7.7 6.8 5.6
Multivitamin supplement use (%) 63.0 68.5 71.9 63.8 67.4 70.7
Current aspirin use (%) 50.2 54.0 52.7 48.8 52.9 54.4
Total energy intake (kcal/day) 1467(481) 1718(495) 2010(537) 1410(457) 1711(466) 2090(533)
Alcohol intake (g/d) 4.9(9.9) 5.2(9.2) 4.8(8.2) 4.4(9.2) 5.2(9.3) 5.4(9.0)
Modified AHEI (score)* 37.9(8.4) 39.2(8.5) 40.9(8.7) 41.4(8.7) 38.8(8.5) 37.8(8.0)
Nurses’ Health Study II (1999)
Number of participants 16,186 16,251 16,011 16,021 16,045 16,039
High-pesticide-residue FVs (servings/d) 0.4(0.1) 1.2(0.1) 2.9(1.2) 0.7(0.6) 1.3(0.8) 2.2(1.3)
Low-pesticide-residue FVs (servings/d) 1.2(0.8) 1.9(0.9) 3.0(1.5) 0.7(0.2) 1.8(0.1) 3.9(1.2)
Total FVs (servings/d) 2.0(1.0) 3.7(1.2) 7.0(2.4) 1.9(1.0) 3.8(1.1) 7.0(2.4)
Age (y) 43.6(4.7) 44.0(4.6) 44.4(4.6) 43.9(4.7) 44.0(4.7) 44.2(4.6)
BMI (kg/m2) 27.1(6.6) 26.3(6.1) 25.9(5.8) 26.9(6.5) 26.3(6.1) 26.0(5.9)
White (%) 95.8 96.8 96.5 95.5 97.0 96.1
Physical activity (MET/wk) 14.0(19.4) 20.1(26.4) 28.5(31.6) 15.7(21.8) 20.0(24.5) 26.5(32.1)
Family history of diabetes (%) 25.4 24.4 24.5 25.1 24.4 24.0
Family history of MI (%) 21.0 20.0 20.4 20.7 20.4 20.1
Current smoker (%) 13.4 8.5 5.7 12.2 8.4 6.5
Premenopausal (%) 77.9 78.1 76.9 76.9 77.9 77.6
Current menopausal hormone users (%) 10.5 10.6 11.1 11.3 11.1 10.6
Oral contraceptive use
 Never user(%) 11.9 13.2 14.8 12.9 13.0 14.7
 Current user (%) 8.9 9.2 8.3 8.8 8.9 8.3
 Past user (%) 79.2 77.6 77.0 78.3 78.1 77.0
Baseline hypertension (%) 14.0 13.2 13.1 13.8 12.4 13.9
Baseline hypercholesterolemia (%) 26.7 24.6 23.6 26.4 24.2 23.6
Baseline diabetes (%) 2.0 2.2 2.4 2.4 2.1 2.0
Multivitamin supplement use (%) 50.4 57.5 63.5 50.8 57.9 63.5
Current aspirin use (%) 17.1 16.9 17.6 16.9 16.6 17.6
Total energy intake (kcal/day) 1547(513) 1813 (522) 2128(556) 1470(477) 1807(492) 2217(544)
Alcohol intake (g/d) 3.5(7.8) 4.1(7.3) 4.2(6.9) 3.3(7.3) 4.0(7.1) 4.3(7.2)
Modified AHEI (score)* 36.9(8.9) 38.4(9.4) 40.8(9.8) 39.9(9.2) 38.5(9.6) 37.5(9.3)
Health Professionals Follow-up Study (1998)
Number of participants 4,864 5,035 4,923 4,876 4,865 4,869
High-pesticide-residue FVs (servings/d) 0.5(0.2) 1.4(0.1) 3.3(1.3) 1.0(0.8) 1.5(0.9) 2.4(1.4)
Low-pesticide-residue FVs (servings/d) 1.6(1.0) 2.4(1.1) 3.4(1.6) 0.9(0.3) 2.2(0.2) 4.5(1.3)
Total FVs (servings/d) 2.7(1.2) 4.7(1.4) 8.1(2.5) 2.6(1.2) 4.7(1.2) 8.2(2.5)
Age (y) 61.6(8.6) 62.8(8.7) 64.2(8.7) 62.1(8.6) 62.9(8.7) 63.1(8.7)
BMI (kg/m2) 26.3(3.6) 26.2(3.6) 25.7(3.5) 26.2(3.5) 26.0(3.5) 25.9(3.6)
White (%) 95.1 95.8 96.1 95.5 96.0 95.4
Physical activity (MET/wk) 26.2(33.1) 35.0(39.1) 47.3(46.6) 28.6(35.3) 35.2(38.1) 44.8(45.5)
Family history of diabetes (%) 21.7 22.7 21.8 21.7 22.4 22.0
Family history of MI (%) 14.8 15.5 14.8 13.7 15.4 14.4
Current smoker (%) 8.2 4.3 2.3 7.4 4.4 3.0
Baseline hypertension (%) 34.4 33.4 30.9 32.5 32.8 33.0
Baseline hypercholesterolemia (%) 46.5 44.8 42.8 44.6 45.1 42.6
Baseline diabetes (%) 5.1 4.8 6.0 6.1 5.5 5.2
Multivitamin supplement use (%) 55.4 59.4 62.6 55.6 59.6 62.9
Current aspirin use (%) 62.8 62.6 62.1 61.9 64.2 62.6
Total energy intake (kcal/day) 1746(558) 1993(582) 2309(642) 1679(528) 1987(548) 2395(636)
Alcohol intake (g/d) 12.0(16.4) 11.3(14.2) 9.9(12.5) 11.1(15.4) 11.4(14.1) 10.6(13.0)
Modified AHEI (Score)* 32.0(8.2) 34.4(7.9) 38.0(8.4) 35.0(8.7) 34.4(8.3) 35.3(8.0)

Values are means (SD) or percentages. All variables except age are age-standardized.

Abbreviations: Modified AHEI, Modified Alternate Healthy Eating Index score; BMI, body mass index; METs: metabolic equivalent tasks; FV: fruits and vegetables; MI: myocardial infarction.

*

Modified AHEI: AHEI-2010, excluding criteria for intakes of fruits and vegetables and alcohol.

METs are defined as the ratio of caloric needed per kilogram of body weight per hour of physical activity divided by the caloric needed per kilogram of body weight at rest.