Table 2.
amh, amhy, and amhr2 mutations in teleost fishes.
Fish amh | |||||
---|---|---|---|---|---|
Species | Allele | Variant | Dominant/recessive | Phenotype | Reference |
zebrafish (Danio rerio) | Exon 6, 5-bp deletion | induced | recessive | enlarged gonads, germ ceil proliferation; female-biased sex ratio | Lin 2017 |
zebrafish (Danio rerio) | Exon 6, 17-bp insertion | induced | recessive | enlarged gonads, germ cell proliferation; female-biased sex ratio | Lin 2017 |
Fish amhy | |||||
Species | Allele | Variant | Dominant/recessive | Phenotype | Reference |
Patagonian pejerrey (Odonthestes hatchteri) | Intron 3, 557-bp insertion | spontaneous | Y-linked | Male to female sex reversal (morpholino knockdown) | Hattori 2012 |
Nile tilapia (Oreochromis niloticus) | Exons 2 and 3, indels (amhΔ-y) | induced | Y-linked | wild-type | Li 2015 |
Nile tilapia (Oreochromis niloticus) | Exons 2 and 3, indels (amhy) | induced | Y-linked | Male to female sex reversal | Li 2015 |
Fish amhr2 | |||||
Species | Allele | Variant | Dominant/recessive | Phenotype | Reference |
Medaka (Oryzias latipes) | Exon 9, Y390C | induced | recessive | enlarged gonads, germ cell proliferation; male to female sex reversal | Morinaga 2007 |
Tiger pufferfish (‘Takifugu rubripes) | Exon 9, H384D | variant | male heterozygotes; female homozygotes | N/A | Kamiya 2012 |
Nile tilapia (Oreochromis niloticus) | Exon 2, indels | induced | recessive | male to female sex reversal | Li 2015 |
Nile tilapia (Oreochromis niloticus) | Exon 3, indels | induced | recessive | male to female sex reversal | Li 2015 |